Results 101 to 110 of about 15,195 (308)
Blood, 2018 Coagulopathy is common in patients with traumatic brain injury (TBI) and predicts poor clinical outcomes. We have shown that brain-derived extracellular microvesicles, including extracellular mitochondria, play a key role in the development of TBI ...
Yuan Zhou +13 more
semanticscholar +1 more source
Advanced Science, EarlyView.These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma +12 more
wiley +1 more source
Endothelial cells release microvesicles that harbour multivesicular bodies and secrete exosomes
Journal of Extracellular Biology, 2023 Extracellular vesicles (EVs) released by endothelial cells support vascular homeostasis. To better understand endothelial cell EV biogenesis, we examined cultured human umbilical vein endothelial cells (HUVECs) prepared by rapid freezing, freeze ...
Jennifer D. Petersen +4 more
doaj +1 more source
Extracellular vesicles: Exosomes, microvesicles, and friends [PDF]
Journal of Cell Biology, 2013 Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively. These extracellular vesicles (EVs) represent an important mode of intercellular communication by serving as vehicles for transfer between cells of membrane and cytosolic proteins ...
Graça Raposo +2 more
openaire +3 more sources
Scientific Reports, 2019 Development of drug resistance in cancer has major implications for patients’ outcome. It is related to processes involved in the decrease of drug efficacy, which are strongly influenced by intratumor heterogeneity and changes in the microenvironment ...
A. Álvarez-Arenas +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Enzymatic introduction of azido‐sialic acid residues to the glycans on exosomes enables a new and efficient approach for exosomal functionalization with various probes, including biotin and fluorophores, by biocompatible click chemistry, thereby facilitating detailed investigations of exosomes, such as their glycan profiles, cellular uptake, etc., and ...
Sayan Kundu +5 more
wiley +1 more source
Ligustrazine monomer against cerebral ischemia-reperfusion injury
Neural Regeneration Research, 2015 Ligustrazine (2,3,5,6-tetramethylpyrazine) is a major active ingredient of the Szechwan lovage rhizome and is extensively used in treatment of ischemic cerebrovascular disease.
Hai-jun Gao +9 more
doaj +1 more source
Individualized Multilayer Tensor Learning with An Application in Imaging Analysis [PDF]
arXiv, 2019 This work is motivated by multimodality breast cancer imaging data, which is quite challenging in that the signals of discrete tumor-associated microvesicles (TMVs) are randomly distributed with heterogeneous patterns. This imposes a significant challenge for conventional imaging regression and dimension reduction models assuming a homogeneous feature ...
arxiv
Microvesicles and intercellular communication in the context of parasitism [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 There is a rapidly growing body of evidence that production of microvesicles (MVs) is a universal feature of cellular life. MVs can incorporate microRNA (miRNA), mRNA, mtDNA, DNA and retrotransposons, camouflage viruses/viral components from immune surveillance, and transfer cargo between cells.
Natasha S. Barteneva +4 more
openaire +4 more sources
Scientific Reports, 2016 Intercellular communications between lung epithelial cells and alveolar macrophages play an essential role in host defense against acute lung injury. Hyperoxia-induced oxidative stress is an established model to mimic human lung injury.
Heedoo Lee +4 more
semanticscholar +1 more source