Results 101 to 110 of about 18,155 (253)
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
Neural Regeneration Research, 2015 Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li +4 more
doaj +1 more source
Tumor cell‐derived vaccines: Advances, challenges, and future prospects
Interdisciplinary Medicine, EarlyView.Classification and Optimization Directions for Tumor Cell‐Derived Vaccines. This diagram systematically illustrates the four major categories of tumor cell‐derived vaccines, along with their core optimization strategies. The upper section presents the four primary vaccine types: autologous/allogeneic whole‐cell vaccines (which preserve the complete ...
Jiaye Lu +9 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Y.EMVs released from young endothelial cells (ECs) prevented vascular aging by ameliorating ECs senescence and dysfunction via regulating miR‐17‐5p, and subsequently inhibited brain aging. O.EMVs released from the senescent ECs played the opposite roles, accompanied with a significant increase of EMVs level and downregulation of miR‐17‐5p encapsulated ...
Huiting Zhang +9 more
wiley +1 more source
Glycan Node Analysis of Plasma-Derived Extracellular Vesicles
Cells, 2020 Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans.
Sierra A. Walker +6 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an increasingly prevalent chronic liver condition that can progress to severe complications such as metabolic dysfunction‐associated steatohepatitis (MASH). Despite its growing burden, there are no reliable non‐invasive biomarkers for tracking disease progression.
Szu‐Jen Wang +9 more
wiley +1 more source
Changes of resting cerebral activities in subacute ischemic stroke patients
Neural Regeneration Research, 2015 This study aimed to detect the difference in resting cerebral activities between ischemic stroke patients and healthy participants, define the abnormal site, and provide new evidence for pathological mechanisms, clinical diagnosis, prognosis prediction ...
Ping Wu +8 more
doaj +1 more source
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup +11 more
wiley +1 more source
Journal of Extracellular Vesicles, 2013 The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease and therapeutic targets.
Kenneth W. Witwer +12 more
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PROTEOMICS, EarlyView.ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq +6 more
wiley +1 more source