Results 111 to 120 of about 16,274 (290)

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

Glycan Node Analysis of Plasma-Derived Extracellular Vesicles

open access: yesCells, 2020
Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans.
Sierra A. Walker   +6 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Changes of resting cerebral activities in subacute ischemic stroke patients

open access: yesNeural Regeneration Research, 2015
This study aimed to detect the difference in resting cerebral activities between ischemic stroke patients and healthy participants, define the abnormal site, and provide new evidence for pathological mechanisms, clinical diagnosis, prognosis prediction ...
Ping Wu   +8 more
doaj   +1 more source

Digital detection of exosomes by interferometric imaging [PDF]

open access: yes, 2016
Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics.
Benussi, Luisa   +13 more
core   +2 more sources

Advanced extracellular vesicle immunotherapy

open access: yesFlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang   +6 more
wiley   +1 more source

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

open access: yesJournal of Extracellular Vesicles, 2013
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease and therapeutic targets.
Kenneth W. Witwer   +12 more
doaj   +1 more source

Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]

open access: yes, 2017
Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J.   +2 more
core   +1 more source

Pharmacological effects of novel microvesicles of basil, on blood glucose and the lipid profile: a preclinical study [PDF]

open access: gold, 2021
Branislava Teofilović   +7 more
openalex   +1 more source

Molecular crosstalk via exosomes in lung cancer progression

open access: yesInterdisciplinary Medicine, EarlyView.
“Molecular and theranostics roles of exosomes in Lung Cancer.” Abstract Exosomes play a critical role in lung cancer metastasis, facilitating tumor progression through intercellular communication between cancer cells and the tumor microenvironment. These nanosized extracellular vesicles carry bioactive molecules such as proteins, nucleic acids, and ...
Rajib Dhar   +3 more
wiley   +1 more source

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