Results 121 to 130 of about 18,155 (253)

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

The FEBS Journal, EarlyView.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou, Sylvia Mangani, Nikolaos E. Koletsis, Christos Koutsakis, Nicholas S. Mastronikolis, Marco Franchi, Nikos K. Karamanos   +6 more
wiley   +1 more source

The Role of miRNAs and Extracellular Vesicles in Adaptation After Resistance Exercise: A Review

Current Issues in Molecular Biology
Resistance exercise can enhance or preserve muscle mass and/or strength. Modifying factors are secreted following resistance exercise. Biomarkers like cytokines and extracellular vesicles, especially small extracellular vesicles, are released into the ...
Dávid Csala, Zoltán Ádám, Márta Wilhelm   +2 more
doaj   +1 more source

Signed, sealed, delivered: microenvironmental modulation of extracellular vesicle-dependent immunoregulation in the lung

Frontiers in Cell and Developmental Biology, 2016
Unconventional secretion and subsequent uptake of molecular cargo via extracellular vesicles (EVs) is an important mechanism by which cells can exert paracrine effects.
Daniel J Schneider, Jennifer M Speth, Marc Peters-Golden, Marc Peters-Golden   +3 more
doaj   +1 more source

Del-etion of Microvesicles From the Circulation [PDF]

, 2012
Pierre‐Emmanuel Rautou, Nigel Mackman
openalex   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

International Journal of Dermatology, EarlyView.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari, Reinaldo Falavigna Tovo, Daniela Franco Bueno   +2 more
wiley   +1 more source

Extracellular Vesicle MicroRNA Transfer in Lung Diseases

Frontiers in Physiology, 2017
MicroRNAs (miRNAs) are single-stranded, small non-coding RNAs that ate involved in the transcriptional and post-transcriptional regulation of gene expression.
Jie Chen, Chengping Hu, Pinhua Pan
doaj   +1 more source

Local protein dynamics during microvesicle exocytosis in neuroendocrine cells

bioRxiv, 2018
Calcium triggered exocytosis is key to many physiological processes, including neurotransmitter and hormone release by neurons and endocrine cells. Dozens of proteins regulate exocytosis, yet the temporal and spatial dynamics of these factors during ...
Agila Somasundaram, Justin W. Taraska
semanticscholar   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Adipose‐Derived Extracellular Vesicles and Intercellular Crosstalk With Skeletal Muscle: Implications for Sarcopenic Obesity and Metabolic Dysregulation

Obesity Reviews, EarlyView.
ABSTRACT Sarcopenic obesity, characterized by the concurrent presence of excess adiposity and diminished skeletal muscle mass and function, is closely linked to frailty, chronic inflammation, and insulin resistance. The increasing prevalence of sarcopenic obesity is driven by the global aging population, widespread adoption of sedentary lifestyles, and
Michael Macleod, Joshua Price, Elpida Tsonou, David J. Baker, Kostas Tsintzas, Simon W. Jones   +5 more
wiley   +1 more source

Megakaryocyte buds are distinct from microvesicles and likely to represent platelet precursors [PDF]

, 2022
Marc Ellis, Imala Alwis, Rhyll E. Smythe, Yuping Yuan, Shaun P. Jackson   +4 more
openalex   +1 more source