Results 11 to 20 of about 15,493 (301)
The ins and outs of microvesicles [PDF]
FASEB BioAdvances, 2021 Microvesicles are a heterogeneous group of membrane-enclosed vesicles that are released from cells into the extracellular space by the outward budding and pinching of the plasma membrane. These vesicles are loaded with multiple selectively sorted proteins and nucleic acids.
James W. Clancy +2 more
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Neutrophil microvesicles and their role in disease [PDF]
The International Journal of Biochemistry & Cell Biology, 2021 Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
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R(h)oads to microvesicles [PDF]
Small GTPases, 2012 A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Marc A. Antonyak +2 more
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Decoding the microvesicle message [PDF]
Nature Reviews Cancer, 2008 Isobel Barry
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The Immunomodulatory Role of Syncytiotrophoblast Microvesicles
PLoS ONE, 2011 Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Jennifer H. Southcombe +3 more
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Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
Nancy Raab-Traub, David G. Meckes
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Microvesicles as immune orchestra conductors
Blood, 2008 In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
Mariusz Z. Ratajczak
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Gut Microbes, 2021 Gut microbiota have myriad roles in host physiology, development, and immunity. Though confined to the intestinal lumen by the epithelia, microbes influence distal systems via poorly characterized mechanisms.
Kevin Champagne-Jorgensen +5 more
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A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity
Frontiers in Cell and Developmental Biology, 2021 Extracellular vesicles (EVs) are emerging mediators of intercellular communication in nonalcoholic steatohepatitis (NASH). Palmitate, a lipotoxic saturated fatty acid, activates hepatocellular endoplasmic reticulum stress, which has been demonstrated to ...
Yasuhiko Nakao +23 more
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Effect of Mesenchymal Stem Cell-derived Microvesicles on Megakaryocytic Differentiation of CD34+ Hematopoietic Stem Cells [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Mesenchymal stem cells (MSCs) release hematopoietic cytokines, growth factors, and Microvesicles (MVs) supporting the hematopoietic stem cells (HSCs).
Sara Aqmasheh +6 more
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