Results 21 to 30 of about 15,493 (301)
Frontiers in Molecular Biosciences, 2021 Respiratory diseases and their comorbidities, such as cardiovascular disease and muscle atrophy, have been increasing in the world. Extracellular vesicles (EVs), which include exosomes and microvesicles, are released from almost all cell types and play ...
Shota Fujimoto +5 more
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Proteomes, 2020 Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion, and microvesicles contribute to transfusion reactions ...
Joames K. Freitas Leal +7 more
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The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick +1 more
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BMC Cancer, 2012 Background RNA from exosomes and other microvesicles contain transcripts of tumour origin. In this study we sought to identify biomarkers of glioblastoma multiforme in microvesicle RNA from serum of affected patients.
Noerholm Mikkel +8 more
doaj +1 more source
Microvesicle Formation Induced by Oxidative Stress in Human Erythrocytes
Antioxidants, 2020 Extracellular vesicles (EVs) released by different cell types play an important role in many physiological and pathophysiological processes. In physiological conditions, red blood cell (RBC)-derived EVs compose 4–8% of all circulating EVs, and oxidative ...
Julia S. Sudnitsyna +5 more
semanticscholar +1 more source
Biology and biogenesis of shed microvesicles [PDF]
Small GTPases, 2016 The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental
Crislyn D'Souza-Schorey +2 more
openaire +3 more sources
Proteomes, 2023 In recent decades, the role played by extracellular vesicles in physiological and pathological processes has attracted attention. Extracellular vesicles are released by different types of cells and carry molecules that could become biomarkers for the ...
Dianny Elizabeth Jimenez +8 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Glioblastoma (GB) is the most aggressive and recurrent form of brain cancer in adults. We hypothesized that the identification of biomarkers such as certain microRNAs (miRNAs) and the circulating microvesicles (MVs) that transport them could be key to establishing GB progression, recurrence and therapeutic response.
Natalia Simionescu +7 more
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Microvesicles as Mediators of Tissue Regeneration [PDF]
Translational Research, 2014 The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Nobuaki Kikyo, Keith Sabin
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Journal of Diabetes Research, 2017 Aims. To investigate how circulating microvesicle phenotypes correlate with insulin sensitivity, body composition, plasma lipids, and hepatic fat accumulation.
Jaco Botha +6 more
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