Results 21 to 30 of about 16,274 (290)

Analysis of the potential of cancer cell lines to release tissue factor-containing microvesicles: correlation with tissue factor and PAR2 expression [PDF]

, 2016
BackgroundDespite the association of cancer-derived circulating tissue factor (TF)-containing microvesicles and hypercoagulable state, correlations with the incidence of thrombosis remain unclear.MethodsIn this study the upregulation of TF release upon ...
A Bharthuar, A Delluc, A Falanga, A Rank, A Rank, AA Khorana, AA Khorana, Anthony Maraveyas, AS Wolberg, BA Lwaleed, C Ettelaie, C Ettelaie, C Hernández, C Sapet, Camille Ettelaie, E Camerer, E Campello, E Cocco, ES Breimo, F Doormaal van, F Langer, GW Tormoen, H Kothari, I Pabinger, J Ahamed, J Thaler, J Thaler, J Thaler, JA Bastarache, JE Geddings, JH Morrissey, John Greenman, K Haubold, KG Livak, L Hu, LV Rao, M Davila, Mary EW Collier, ME Collier, ME Collier, ME Collier, ME Collier, ME Tesselaar, ML Rand, N Satta, N Tavoosi, Naima E. Benelhaj, NS Key, P Bucciarelli, R Flaumenhaft, RI Kushak, S Butenas, SJ Compton, SK Dasgupta, Sophie Featherby, T Kawamoto, V Combes, W Ruf   +57 more
core   +2 more sources

Exercise-Derived Microvesicles: A Review of the Literature [PDF]

, 2018
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent, Rakobowchuk, Mark, Wilhelm, Eurico N.   +2 more
core   +2 more sources

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth [PDF]

, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in human and ...
Anderson, Kurt I., Helbig, Lena, Julian, Linda, Kadir, Shereen, Kalna, Gabriela, McGhee, Ewan J., Morton, Jennifer P., Mullin, Margaret, Olson, Michael F., Pinho, Andreia V., Rath, Nicola, Rooman, Ilse, Samuel, Michael S.   +12 more
core   +1 more source

Receptor-Dependent and -Independent Effects of Hemin on Platelet Plasma Membrane Disintegration. [PDF]

FASEB J
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Laspa Z, Rohlfing AK, Hochuli R, Sowa PW, Castor T, Gawaz MP.   +5 more
europepmc   +2 more sources

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source

Infrared Nanospectroscopy of Individual Extracellular Microvesicles [PDF]

Molecules, 2021
Extracellular vesicles are membrane-delimited structures, involved in several inter-cellular communication processes, both physiological and pathological, since they deliver complex biological cargo. Extracellular vesicles have been identified as possible biomarkers of several pathological diseases; thus, their characterization is fundamental in order ...
Polito, Raffaella, Musto, Mattia, Temperini, Maria Eleonora, Ballerini, Laura, Ortolani, Michele, Baldassarre, Leonetta, Casalis, Loredana, Giliberti, Valeria   +7 more
openaire   +3 more sources

Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy

Journal of Diabetes Research, 2017
Aims. To investigate how circulating microvesicle phenotypes correlate with insulin sensitivity, body composition, plasma lipids, and hepatic fat accumulation.
Jaco Botha, Line Velling Magnussen, Morten Hjuler Nielsen, Tine Bo Nielsen, Kurt Højlund, Marianne Skovsager Andersen, Aase Handberg   +6 more
doaj   +1 more source

Circulating Extracellular Vesicles and Endothelial Damage in Sickle Cell Disease

Frontiers in Physiology, 2020
Endothelial damage is central to the pathogenesis of many of the complications of sickle cell disease. Circulating extracellular vesicles (EVs) have been implicated in modulating endothelial behavior in a variety of different, diseases with vascular ...
Gabrielle Lapping-Carr, Joanna Gemel, Yifan Mao, Eric C. Beyer   +3 more
doaj   +1 more source

Whole-body heat stress and exercise stimulate the appearance of platelet microvesicles in plasma with limited influence of vascular shear stress [PDF]

, 2017
Intense, large muscle mass exercise increases circulating microvesicles, but our understanding of microvesicle dynamics and mechanisms inducing their release remains limited.
Chiesa, Scott T., González-Alonso, José, Kalsi, Kameljit K., Rakobowchuk, Mark, Trangmar, Steven J., Wilhelm, Eurico N.   +5 more
core   +5 more sources

Cellular phenotype switching and microvesicles [PDF]

Advanced Drug Delivery Reviews, 2010
Cell phenotype alteration by cell-derived vesicles presents a new aspect for consideration of cell fate. Accumulating data indicates that vesicles from many cells interact with or enter different target cells from other tissues, altering their phenotype toward that of the cell releasing the vesicles.
Peter J, Quesenberry, Jason M, Aliotta
openaire   +2 more sources