Results 21 to 30 of about 15,195 (308)

Effect of Mesenchymal Stem Cell-derived Microvesicles on Megakaryocytic Differentiation of CD34+ Hematopoietic Stem Cells [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: Mesenchymal stem cells (MSCs) release hematopoietic cytokines, growth factors, and Microvesicles (MVs) supporting the hematopoietic stem cells (HSCs).
Sara Aqmasheh, Karim Shamsasenjan, Elham Khalaf Adeli, Aliakbar Movassaghpourakbari, Parvin Akbarzadehlaleh, Davod Pashoutan Sarvar, Hamzeh Timari   +6 more
doaj   +1 more source

Intercellular Communication by Vascular Endothelial Cell-Derived Extracellular Vesicles and Their MicroRNAs in Respiratory Diseases

Frontiers in Molecular Biosciences, 2021
Respiratory diseases and their comorbidities, such as cardiovascular disease and muscle atrophy, have been increasing in the world. Extracellular vesicles (EVs), which include exosomes and microvesicles, are released from almost all cell types and play ...
Shota Fujimoto, Yu Fujita, Yu Fujita, Tsukasa Kadota, Jun Araya, Kazuyoshi Kuwano   +5 more
doaj   +1 more source

The biology of extracellular microvesicles [PDF]

Traffic, 2018
The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick, Crislyn D'Souza‐Schorey   +1 more
openaire   +2 more sources

Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences

Proteomes, 2020
Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion, and microvesicles contribute to transfusion reactions ...
Joames K. Freitas Leal, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, Giel Bosman   +7 more
doaj   +1 more source

Ligamentum arteriosum and its telocytes: An ultrastructure description

The Anatomical Record, Volume 306, Issue 1, Page 187-192, January 2023., 2023
Abstract Results from my study have shown in 2022 the existence of telocytes (TCs) in mice ligamentum arteriosum (LA). Telocytes (TCs) are unique interstitial or stromal cells of mesodermal origin, defined by long cellular extensions called telopodes (Tps) which form a network, connecting them to surrounding cells. These Tps have dilated portions named
Benedicta Quaye Mensah
wiley   +1 more source

RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

BMC Cancer, 2012
Background RNA from exosomes and other microvesicles contain transcripts of tumour origin. In this study we sought to identify biomarkers of glioblastoma multiforme in microvesicle RNA from serum of affected patients.
Noerholm Mikkel, Balaj Leonora, Limperg Tobias, Salehi Afshin, Zhu Lin, Hochberg Fred H, Breakefield Xandra O, Carter Bob S, Skog Johan   +8 more
doaj   +1 more source

Microvesicle Formation Induced by Oxidative Stress in Human Erythrocytes

Antioxidants, 2020
Extracellular vesicles (EVs) released by different cell types play an important role in many physiological and pathophysiological processes. In physiological conditions, red blood cell (RBC)-derived EVs compose 4–8% of all circulating EVs, and oxidative ...
Julia S. Sudnitsyna, E. Skverchinskaya, I. Dobrylko, E. Nikitina, S. Gambaryan, I. Mindukshev   +5 more
semanticscholar   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Microvesicles and Cancer Associated Thrombosis [PDF]

Seminars in Thrombosis and Hemostasis, 2019
AbstractMicrovesicles (MVs) are small membrane enclosed structures released into the extracellular space by virtually all cell types. Their composition varies according to the cell origin and the stimulus which caused their formation. They harbor functional molecules and participate in intercellular communication.
Lacroix, Romaric, Vallier, Loris, Bonifay, Amandine, Simoncini, Stephanie, Mege, Diane, Aubert, Mathilde, Panicot-Dubois, Laurence, Dubois, Christophe, Dignat-George, Francoise   +8 more
openaire   +6 more sources

Molecular and cellular paradigms of multidrug resistance in cancer

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya, Abu Sufiyan Chhipa, Vinita Mishra, Vishal Kumar Gupta, Shiv Govind Rawat, Ajay Kumar, Chandramani Pathak   +6 more
wiley   +1 more source