Results 41 to 50 of about 6,907 (199)
IntroductionCurrently there are no biomarkers that are predictive of when patients with type-2 diabetes (T2D) will progress to more serious kidney disease i.e., diabetic nephropathy (DN).
Carla Harkin +11 more
doaj +1 more source
Midkine Deficiency Attenuates Lipopolysaccharide-Induced Pulmonary Inflammation. [PDF]
Midkine (MDK) is a multifunctional heparin-binding growth factor, and has been shown to regulate cell growth, survival and migration. It also plays important roles in several inflammatory diseases such as sepsis. However, the role of MDK in the lungs has not yet been elucidated.
Tanino Y +8 more
europepmc +3 more sources
Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival [PDF]
LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology.
Gilder, Andrew S. +4 more
core +3 more sources
Objective: Hypertension (HT) is one of the risk factors associated with dementia. Our aim was to research cognitive functions in patients with HT and its relationship to midkine levels in serum.
Eda Celik Guzel +8 more
doaj +1 more source
Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus [PDF]
Pleiotrophin (PTN) is a secreted growth factor, and also a cytokine, associated with the extracellular matrix, which has recently starting to attract attention as a significant neuromodulator with multiple neuronal functions during development.
González Castillo, Celia +4 more
core +2 more sources
Mycophenolic acid (MPA) is prescribed to prevent allograft rejection in organ transplanted patients. However, its use is sporadically linked to leak flux diarrhea and other gastrointestinal (GI) disturbances in around 75% of patients through yet unknown ...
Niamat Khan +7 more
doaj +1 more source
Different classes of phytochemicals were previously isolated from the Red Sea algae Hypnea musciformis as sterols, ketosteroids, fatty acids, and terpenoids. Herein, we report the isolation of three fatty acids—docosanoic acid 4, hexadecenoic acid 5, and
Sameh S. Elhady +13 more
doaj +1 more source
Chondroitin sulfates and their binding molecules in the central nervous system [PDF]
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a ...
Djerbal, L, Kwok, JCF, Lortat-Jacob, H
core +3 more sources
Hippocampal Gene Expression Is Highly Responsive to Estradiol Replacement in Middle-Aged Female Rats. [PDF]
In the hippocampus, estrogens are powerful modulators of neurotransmission, synaptic plasticity and neurogenesis. In women, menopause is associated with increased risk of memory disturbances, which can be attenuated by timely estrogen therapy.
Annie Rodolosse +7 more
core +1 more source
Involvement of midkine in neuroblastoma tumourigenesis [PDF]
Midkine is highly expressed in various cancers, including neuroblastoma, one of the most malignant paediatric solid tumours known. Also, it has been shown to be useful as a tumour marker, a prognosis factor and a target of molecular therapy. Several molecular tools (e.g.
S, Kishida, K, Kadomatsu
openaire +2 more sources

