Results 51 to 60 of about 6,987 (195)
Hippocampal Gene Expression Is Highly Responsive to Estradiol Replacement in Middle-Aged Female Rats. [PDF]
, 2015 In the hippocampus, estrogens are powerful modulators of neurotransmission, synaptic plasticity and neurogenesis. In women, menopause is associated with increased risk of memory disturbances, which can be attenuated by timely estrogen therapy.
Annie Rodolosse +7 more
core +1 more source
Midkine can not be accepted as a new biomarker for unexplained female infertility
Türk Biyokimya Dergisi, 2023 This study aimed to investigate whether a growth factor and a cytokine midkine (MK) can be a new biomarker for the diagnosis and treatment of unexplained female infertility (UFI) cases.
Ergüven Mine +3 more
doaj +1 more source
Involvement of midkine in neuroblastoma tumourigenesis [PDF]
British Journal of Pharmacology, 2014 Midkine is highly expressed in various cancers, including neuroblastoma, one of the most malignant paediatric solid tumours known. Also, it has been shown to be useful as a tumour marker, a prognosis factor and a target of molecular therapy. Several molecular tools (e.g.
S, Kishida, K, Kadomatsu
openaire +2 more sources
Biomarkers for Hepatocellular Carcinoma [PDF]
, 2017 Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. The HCC diagnosis is usually achieved by biomarkers, which can also help in prognosis prediction.
Jiang, Shuai +4 more
core +2 more sources
Advanced Science, EarlyView.Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng +12 more
wiley +1 more source
Antioxidants, 2021 A possibility of repurposing sitagliptin, a well-established antidiabetic drug, for alleviating injury caused by ischemia-reperfusion (IR) is being researched.
Małgorzata Trocha +7 more
doaj +1 more source
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
Advanced Science, EarlyView.This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
Dienogest mediates midkine suppression in endometriosis [PDF]
Human Reproduction, 2016 What are the effects of dienogest (DNG) on midkine (MK) production in women with endometriosis?DNG-mediated down-regulation of MK in vivo and in vitro.DNG is an oral progestin that alleviates painful symptoms of women with endometriosis with a favourable tolerability and safety profile. Its effects on MK, a growth factor that plays an important role in
Nirgianakis, K +5 more
openaire +8 more sources
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis
Arthritis Research & Therapy, 2018 Background Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is one of the leading causes of death in SSc. Identification of a serum-based proteomic diagnostic biomarker for SSc-PAH would allow for rapid non-invasive screening and ...
Lisa M. Rice +9 more
doaj +1 more source
European Journal of Inflammation, 2020 Midregional pro-adrenomedullin (MR-proADM), midkine, and stromelysin2 (ST2) are novel cardiac biomarkers associated with heart failure and atherosclerotic diseases like stable ischemic disease and acute coronary syndrome.
Zhong Chen, Yawen Zhu, Lili Zhang
doaj +1 more source