Results 41 to 50 of about 2,564 (146)
Midkine’s Role in Cardiac Pathology
Journal of Cardiovascular Development and Disease, 2017 Midkine (MDK) is a heparin-binding growth factor that is normally expressed in mid-gestational development mediating mesenchymal and epithelial interactions. As organisms age, expression of MDK diminishes; however, in adults, MDK expression is associated
Kathleen C. Woulfe, Carmen C. Sucharov
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Additional file 1 of Midkine promotes glioblastoma progression via PI3K-Akt signaling
, 2021 Additional file 1: Figure S1. The COIP of MDK and its target. COIP of MDK and its target. MDK was transfected into A172 cells respectively. Immunoprecipitation was performed by XRN2, TCF12 and SP1 antibody and immunoblotting.
Xianlun Mo (11474613) +8 more
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Proangiogenic factor midkine is increased in melanoma patients with sleep apnea and induces tumor cell proliferation [PDF]
, 2021 Midkine (MDK) might mediate the proangiogenic effect of intermittent hypoxia (IH) in patients with obstructive sleep apnea (OSA) and cutaneous melanoma (CM).
Pastor, Esther +23 more
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Midkine promotes glioblastoma progression via PI3K-Akt signaling
Cancer Cell International, 2021 Background Our previous bioinformatics-based study found that midkine (MDK) was associated with poor prognosis of glioblastoma (GBM). However, the mechanism of MDK in GBM remains elusive.
Beiquan Hu +8 more
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Midkine in Advanced Prostate Cancer - Biological Impact and Biomarker Potential [PDF]
, 2017 Prostate cancer (PC) is generally an androgen-driven disease, why androgen deprivation therapy (ADT) is the cornerstone for treatment of advanced and metastatic hormone-naïve PC (HNPC).
Nordin, Anna
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The Growth Factor Midkine Antagonizes VEGF Signaling In Vitro and In Vivo
Neoplasia: An International Journal for Oncology Research, 2008 Midkine (MDK) is a heparin-binding growth factor involved in growth, survival, migration, and differentiation of various target cells and dysregulation of MDK signaling is implicated in a variety of inflammatory diseases and cancers.
Edward Htun van der Horst +8 more
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Journal of Interventional Medicine, 2021 Objective: To explore the clinical significance of serum midkine (MDK) levels for the diagnosis of hepatocellular carcinoma (HCC) and evaluate the efficacy of interventional therapy.
Lin Zheng +7 more
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Biomedicines, 2022 Ovarian cancer (OC) is a particularly lethal disease due to intratumoral heterogeneity, resistance to traditional chemotherapy, and poor response to targeted therapy and immunotherapy.
Qun Liu +9 more
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Plasma midkine (MDK) concentrations in healthy children.
, 2019 Plasma was obtained from healthy, non-obese children younger than 18 years (n = 222) from the United States or South Korea. Plasma midkine concentration was measured by sandwich enzyme-linked immunosorbent assay (ELISA).
Jack A. Yanovski (7542557) +11 more
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iScienceSummary: Lymph node metastasis (LNM) is the main metastatic pathway of cervical cancer, which is closely related to 5-year survival rate of cervical squamous cell carcinoma (CSCC), yet the underlying mechanism remains unconfirmed.
He Fei, Tong Chen, Hua Jiang
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