Results 71 to 80 of about 2,564 (146)
Midkine-antibody (Mdk-Ab) treatment accelerated osteoporotic fracture healing.
, 2016 Biomechanical, micro-computed tomography (μCT) and histomorphometric analysis of the fractured femurs at day 23. Biomechanical testing: A) relative flexural rigidity of the fractured femur in comparison with intact femur determined by biomechanical ...
Katja Prystaz (3154410) +9 more
core +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
The Journal of Pathology, Volume 268, Issue 2, Page 200-214, February 2026.Abstract Cervical cancer remains the fourth most common cancer affecting women worldwide, and incidences of other HPV‐related cancers continue to rise. For the development of effective prevention strategies in high‐risk patients, we aimed to better understand the roles of inflammatory pathways and the tumour microenvironment as the main driver of ...
Gianna Pavilion +9 more
wiley +1 more source
, 2011 There is considerable evidence showing that the neurodegenerative processes that lead to sporadic Parkinson`s disease (PD) begin many years before the appearance of the characteristic motor symptoms and that impairments in olfactory, cognitive and motor ...
Aderbal S. Aguiar +21 more
core +1 more source
International Journal of Genomics, Volume 2026, Issue 1, 2026.Background The tumor microenvironment (TME) plays a crucial role in the development and progression of laryngeal squamous cell carcinoma (LSCC). However, the mechanisms by which aggrephagy reshapes the TME remain unclear. Materials and Methods Single‐cell RNA sequencing (scRNA‐seq) and bulk RNA sequencing (bulk RNA‐seq) data of LSCC were obtained from ...
Hui-min Xu +5 more
wiley +1 more source
Table_1_Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins.docx
, 2022 IFN-γ is a pleiotropic cytokine with immunomodulatory and tumoricidal functions. It has been used as an anti-tumor agent in adjuvant therapies for various cancers.
Tao Wen (304736) +9 more
core +1 more source
Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.We provide the first single‐cell atlas of the human decidua in advanced maternal age (AMA). A novel PRR15‐TGF‐β axis is identified, where PRR15 loss drives stromal fibrosis and decidualisation failure. This study reveals that AMA‐associated uterine fibrosis begins in the first trimester, shifting focus to maternal factors.
Hongliang Xie +13 more
wiley +1 more source
, 2018 Wir untersuchten in der vorliegenden Arbeit anhand eines etablierten murinen Frakturheilungsmodells den Einfluss eines Anti-Midkine-Antikörpers (Anti-MDK- AK) auf die Frakturheilung.
Rößler, Robin
core +1 more source
TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer
iMetaOmics, Volume 2, Issue 4, December 2025.This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin +7 more
wiley +1 more source
Lipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC
Cell ReportsSummary: Leptomeningeal metastases (LMs) remain a devastating complication of non-small cell lung cancer (NSCLC), particularly following osimertinib resistance.
Yang-Si Li +29 more
doaj +1 more source