Results 281 to 290 of about 2,300,834 (356)

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Milk and Milk Products

Journal of Dairy Science, 1930
openaire   +2 more sources

Online Coupling of Field-Flow Fractionation with Raman Microspectroscopy Enables the Advanced Study of Nanoplastics Directly in Food. [PDF]

Anal Chem
Giordani S, Huber MJ, Jüngling IS, Zattoni A, Roda B, Reschiglian P, Marassi V, Ivleva NP.   +7 more
europepmc   +1 more source

Steap4 Promotes Senile Osteoporosis via Fe2+‐ROS/C/EBPβ Feedback‐Driven Ferroptosis and Adipogenesis in Senescent BMSCs

Advanced Science, EarlyView.
Senescent bone marrow mesenchymal stem cells (BMSCs) exhibit increased sensitivity to ferroptosis, a phenomenon associated with Steap4, a nicotinamide adenine dinucleotide phosphate hydrogen (NADPH)‐dependent metalloreductase that reduces Fe3+ to Fe2+.
Liangliang Wang, Guangrong Yin, Wenming Li, Maoyuan Li, Feng Lu, Chao Xu, Gongyin Zhao, Dechun Geng, Jiaxiang Bai, Yuji Wang   +9 more
wiley   +1 more source

Diet, gut microbiome, and type 1 diabetes: from risk to translational opportunity. [PDF]

Gut Microbes
Girdhar K, Dedrick S, Rhodes L, Kim D, Powis A, Mahon C, Chapdelaine H, Obaid L, McNamara M, Altindis E.   +9 more
europepmc   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

Human milk banking services: An umbrella review protocol. [PDF]

HRB Open Res
O'Donovan R, Long A, Lehane E, Mulcahy H, Ward S, Murphy M, Rogers S, Weaver G, Leahy-Warren P.   +8 more
europepmc   +1 more source

Artificial Tactile Perception System for Exploring Internal and External Features of Objects via Time‐Frequency Features

Advanced Science, EarlyView.
By engaging in different active exploration behaviors, the tactile perception system can generate distinct signal modes, enabling the application of targeted decoding strategies for efficient and accurate perception of both external and internal object features.
Yuanzhi Zhou, Jingqi Zhang, Linyi Li, Muxing Huang, Ziyi Zhang, Xingmin Lu, Zilan Li, Xuchun Gui, Xinming Li   +8 more
wiley   +1 more source

Effect of Supplemental Bamboo Leaf Extract on Milk Production, Composition, Biochemical Indices, and Fecal Microbiota Diversity in Grazing <i>Yili</i> Mares. [PDF]

Life (Basel)
Wang C, Wang J, Ma B, Liu T, Yuan X, Meng J, Zeng Y.   +6 more
europepmc   +1 more source