Abstract Aims Despite therapeutic advancements, the prognosis of heart failure (HF) remains poor, with high rates of mortality and readmission, particularly following a HF exacerbation. This study aimed to evaluate the effects of a nurse‐coordinated multidisciplinary comprehensive HF management programme on HF patients.
Cecilia Miu‐Ching Chan +13 more
wiley +1 more source
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease [PDF]
Atsushi Sato, Kenshi Hayashi, T Saruta
openalex +1 more source
Novel antihypertensive action of rutin is mediated via inhibition of angiotensin converting enzyme/mineralocorticoid receptor/angiotensin 2 type 1 receptor (ATR1) signaling pathways in uninephrectomized hypertensive rats [PDF]
openalex +1 more source
Soluble urokinase plasminogen activator receptor and outcomes in HFpEF: A TOPCAT ancillary study
Abstract Aims Inflammation is postulated to be a key pathogenic mechanism in heart failure with preserved ejection fraction (HFpEF). Soluble urokinase plasminogen activator receptor (suPAR), a regulator of innate immune activity, is associated with incident heart failure; however, its role in HFpEF remains unclear.
Christina G. Hutten +9 more
wiley +1 more source
Glucocorticoid and mineralocorticoid receptors regulate paracellular permeability in a primary cultured gill epithelium [PDF]
Scott P. Kelly, Helen Chasiotis
openalex +1 more source
Abstract Purpose Finerenone, a highly selective non‐steroidal mineralocorticoid receptor antagonist, was approved for the treatment of patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (diabetic kidney disease, DKD). Finerenone reduced the composite endpoint of heart failure events and cardiovascular death in patients with heart ...
Kristian Hellenkamp +9 more
wiley +1 more source
Qué sabemos sobre las consecuencias a largo plazo de la separación materna temprana y la respuesta neuroendocrina al estrés [PDF]
Adverse conditions during early life are a risk factor for stress-related diseases. How this early adversity induce long-term effects is not well understood, however there are several evidence that the stress hormones play a determining role.
Renard, Georgina Maria +1 more
core
Modulation of Immunity and Inflammation by the Mineralocorticoid Receptor and Aldosterone [PDF]
Natalia Muñoz‐Durango +6 more
openalex +1 more source
Modulation of transcriptional mineralocorticoid receptor activity by casein kinase 1 [PDF]
Stefanie Ruhs +21 more
openalex +1 more source
In a prospective, randomized study of high‐risk HF patients, simultaneous vaccination against influenza and RSV reduced the risk of the primary composite endpoint (hospitalization for HF, all‐cause death, or infection). The main driver of benefit was a lower incidence of infections.
Jan Biegus +14 more
wiley +1 more source

