Results 161 to 170 of about 61,117 (342)
Temporal trends in initiation of mineralocorticoid receptor antagonists and risk of subsequent withdrawal in patients with heart failure: a nationwide study in
, 2021 Deewa Zahir +12 more
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Internal Medicine Journal, EarlyView.Abstract Background Previous studies have identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF). Aims This study aims to identify distinct phenotypes in older patients with HFpEF hospitalised for acute heart failure (AHF) and investigate the relationship between subgroups and outcomes ...
Maria Livia Burzo * +10 more
wiley +1 more source
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease [PDF]
, 2005 Atsushi Sato, Kenshi Hayashi, T Saruta
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The biology of PKM2 in the metabolism and senescence in diabetic kidney disease
Journal of Diabetes Investigation, EarlyView.ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley +1 more source
Need to Revisit Heart Failure Treatment Guidelines for Hyperkalaemia Management During the Use of Mineralocorticoid Receptor Antagonists [PDF]
, 2018 Javed Butler +2 more
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Journal of Diabetes Investigation, EarlyView.Bifidobacterium bifidum G9‐1 improved stool form, defecation frequency, and Quality of Life in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation. ABSTRACT Introduction Although constipation is a major complication of type 2 diabetes mellitus and chronic kidney disease, evidence for its treatment in these ...
Fuki Ikeda +10 more
wiley +1 more source
Journal of Fish Biology, EarlyView.Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe +4 more
wiley +1 more source
Mineralocorticoid receptor antagonists modulate ST2 signaling pathway in chronic heart failure [PDF]
, 2013 M. Lopez +9 more
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Obesity Reviews, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves +8 more
wiley +1 more source