Results 41 to 50 of about 26,068 (276)

Persistent hypoaldosteronism post-adrenalectomy for primary aldosteronism – a role for pre-operative spironolactone?

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2021
Primary aldosteronism is one of the most common (affecting up to 10%) yet treatable causes of hypertension in our community, notable due to an associated elevated risk of atrial fibrillation, stroke and myocardial infarction compared to essential ...
Lachlan M Angus, Jun Yang, Ada S Cheung
doaj   +1 more source

Mineralocorticoid receptor blockade during a rat's first violent encounter inhibits its subsequent propensity for violence. [PDF]

open access: yes, 2013
In individuals naive to serious conflict in an unfamiliar environment, violence has long-lasting effects on subsequent aggressive behavior. This effect of the stressful experience of a first violent conflict occurs in victims as well as offenders.
Haller, József   +3 more
core   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

open access: yes, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A   +2 more
core   +2 more sources

Mineralocorticoid Receptor Antagonist for Renal Protection

open access: yesRenal Failure, 2012
The renin-angiotensin system (RAS) plays an important role in the pathophysiology of cardiovascular and renal diseases. In chronic kidney disease (CKD), blockade of RAS by angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) has been shown to reduce proteinuria and retard the progression of renal function deterioration ...
Terry King-Wing, Ma, Cheuk-Chun, Szeto
openaire   +2 more sources

Network meta-analysis of mineralocorticoid receptor antagonists for diabetic kidney disease

open access: yesFrontiers in Pharmacology, 2022
Diabetic kidney disease (DKD) is one of the major causes of end-stage renal disease (ESRD). To evaluate the efficacy and safety of different types of mineralocorticoid receptor antagonists (MRAs) in diabetic kidney disease patients, we conducted this ...
Yichuan Wu   +13 more
doaj   +1 more source

Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]

open access: yes, 2016
10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia   +4 more
core   +1 more source

Regulation of Klotho Production by Mineralocorticoid Receptor Signaling in Renal Cell Lines

open access: yesBiomolecules
Through the mineralocorticoid receptor, aldosterone controls extracellular volume and arterial blood pressure by stimulating Na+ absorption and K+ secretion in epithelial cells of the kidney, colon, and several glands.
Elena Kohm   +2 more
doaj   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

open access: yes, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF   +3 more
core   +2 more sources

Parathyroid localization [PDF]

open access: yes, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.   +7 more
core   +1 more source

Mineralocorticoid Receptor Antagonists for Diabetic Kidney Disease [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2020
Ten years ago, I presented an outline for a study aiming to prevent diabetic kidney disease (DKD), with early intervention in subjects with type 2 diabetes and high risk for DKD assessed by a urinary proteomic–based biomarker, at Kidney Week hoping for positive feedback.
openaire   +3 more sources

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