Results 61 to 70 of about 25,411 (262)

Adecuación en España a las recomendaciones terapéuticas de la guía de la ESC sobre insuficiencia cardiaca: ESC Heart Failure Long-term Registry [PDF]

, 2015
[Abstract] Introduction and objectives. To estimate the percentage of heart failure patients in Spain that received the European Society of Cardiology recommended treatments, and in those that did not, to determine the reasons why. Methods.
Almenar-Bonet, Luis, Bayes-Genis, Antoni, Crespo-Leiro, María Generosa, Delgado-Jiménez, Juan F., Fernández-Vivancos, Carla, Fuente Galán, Luis de la, García-Pinilla, José Manuel, González-Costello, José, Lara-Padrón, Antonio, López-Fernández, Silvia, Mora-Martín, Manuel de, Roig, Eulàlia, Sanz-Julve, Marisa, Segovia Cubero, Javier, Varela-Román, Alfonso   +14 more
core   +2 more sources

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition and Cancer Risk: Insights from a Large Propensity‐Matched Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon, Chen Gurevitz, Tzippy Shochat, Shiri Kushnir, Guy Witberg, Amos Levi, Dan Gilon, Ran Kornowski, Paaladinesh Thavendiranathan, Husam Abdel Qadir, Zaza Iakobishvili   +10 more
wiley   +1 more source

Pharmacotherapy of resistant arterial hypertension [PDF]

Терапевтический архив, 2018
Pharmacotherapy of resistant arterial hypertension represents a serious problem, because today there are no clear algorithms of action in this clinical situation. The review discusses the key works in which the authors propose a solution to this problem.
N E Shepeleva, A V Rodionov, V V Fomin
doaj   +3 more sources

Evidence for Aldosterone Antagonism in Heart Failure

Cardiac Failure Review
Activation of the renin–angiotensin–aldosterone system is the ultimate pathophysiological hallmark in heart failure. Though aldosterone primarily appears to regulate electrolyte homeostasis by acting on distal nephrons in the kidneys, its effects are far-
Rishi Sethi, Pravesh Vishwakarma, Akshyaya Pradhan   +2 more
doaj   +1 more source

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source

Why are mineralocorticoid receptor antagonists cardioprotective? [PDF]

Naunyn-Schmiedeberg's Archives of Pharmacology, 2006
Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown that mineralocorticoid receptor (MR) antagonists reduce mortality in patients with heart failure on top of ACE inhibition.
Chai, W (Wenxia), Danser, Jan
openaire   +3 more sources

Socio‐economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis

ESC Heart Failure, Volume 12, Issue 2, Page 927-941, April 2025.
Abstract Socio‐economic status (SES) has been associated with incident and prevalent heart failure (HF), as well as its morbidity and mortality. However, the precise nature of the relationship between SES and HF remains unclear due to inconsistent data. This study aims to provide a comprehensive assessment and data synthesis of the relationship between
Abdul Shakoor, Willemijn A. van Maarschalkerwaart, Jeroen Schaap, Rudolf A. de Boer, Nicolas M. van Mieghem, Eric H. Boersma, Loek van Heerebeek, Jasper J. Brugts, Robert M.A. van der Boon   +8 more
wiley   +1 more source

Aldosterone Synthase Inhibitors for Cardiorenal Protection: Ready for Prime Time?

Kidney & Blood Pressure Research
Background: Aldosterone is the principal mineralocorticoid hormone and the final effector of the renin-angiotensin-aldosterone system. This hormone is primarily synthesized by the CYP11B2 enzyme and produced by the adrenal zona glomerulosa ...
Alessio Mazzieri, Francesca Timio, Francesco Patera, Francesco Trepiccione, Mario Bonomini, Gianpaolo Reboldi   +5 more
doaj   +1 more source

Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation [PDF]

, 2005
Prova tipográfica (In Press)An important question arising from previous observations in vivo is whether glucocorticoids can directly influence neuronal survival in the hippocampus.
AHS Hassan, AM Magarinos, C Behl, C Crochemore, C Crochemore, CD Hornsby, CM Beamen-Hall, CS Woolley, D Jaarsma, D Obradovic, D Pearce, DM Vázquez, E Fuchs, EM Elliott, ER de Kloet, ER de Kloet, F Holsboer, F Holsboer, H Coirini, HA Cameron, J Lu, J Lu, J Lu, JM Reul, JM Reul, LA Welberg, LE Haynes, LE Haynes, LP Reagan, M Tirard, MI Schubert, MN Starkman, N Sousa, N Sousa, N Sousa, N Sousa, N Sousa, N Sousa, N Sousa, O F X Almeida, OFX Almeida, P Nirde, P Rosenfeld, PJ Kim, PJ Lucassen, PW Gold, R Alzamora, RM Sapolsky, RM Sapolsky, RS Sloviter, RS Sloviter, S Hellbach, SJ Lupien, Y Gavrieli, Y Wu, YI Sheline, Z Hu, Z Liposits, Z Liposits   +58 more
core   +1 more source

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

ESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen, Aldina Pivodic, Maria Schaufelberger, Annika Rosengren, Michael Fu   +4 more
wiley   +1 more source