Results 1 to 10 of about 6,635 (208)

MNS16A tandem repeats minisatellite of human telomerase gene and cancer risk: a meta-analysis. [PDF]

open access: goldPLoS ONE, 2013
BACKGROUND: Researchers have provided evidence that telomere dysfunction play an important role in cancer development. MNS16A is a polymorphic tandem repeats minisatellite of human telomerase (hTERT) gene that influences promoter activity of hTERT and ...
Xiaoping Xia   +12 more
doaj   +5 more sources

Molecular Identification of Genetic Diversity and Population Structure in Moroccan Male Date Palm (Phoenix dactylifera L.) Using Inter-Simple Sequence Repeat, Direct Amplification of Minisatellite DNA, and Simple Sequence Repeat Markers [PDF]

open access: goldHorticulturae
Understanding genetic diversity and population structure plays a vital role in the efficient use of available material in plant-breeding programs and in germplasm conservation strategies.
Maha Ibrahimi   +10 more
doaj   +2 more sources

Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase. [PDF]

open access: goldNucleic Acids Res, 2005
Repeating DNA sequences, such as telomeres, centromeres, and micro- and mini-satellites, comprise 50% of the genome and play important roles in regulatory and pathogenic mechanisms. In order to study structures and functions of such repeating sequences, it is important to have simple and efficient methods for making them in vitro. Here, we describe the
Hartig JS, Kool ET.
europepmc   +6 more sources

Pytrf: a python package for finding tandem repeats from genomic sequences [PDF]

open access: yesBMC Bioinformatics
Background Tandem repeats (TRs) are major sources of genetic variation and important genetic markers. Their expansions are not only involved in gene expression regulation but also associated with many nervous system diseases and cancers.
Lianming Du   +6 more
doaj   +2 more sources

Exploring the Genetic Variability of Gmelina arborea Roxb. in Mexico with Molecular Markers to Establish an Efficient Improvement Program [PDF]

open access: yesPlants
Melina (Gmelina arborea Roxb.) is a tree native to Asia, whose timber is not utilized in that region for a variety of reasons. However, the tree’s fast growth and extensive range of applications have increased its acceptance in other world’regions.
Marynor E. Ortega-Ramírez   +6 more
doaj   +2 more sources

IGS Minisatellites Useful for Race Differentiation in Colletotrichum lentis and a Likely Site of Small RNA Synthesis Affecting Pathogenicity. [PDF]

open access: yesPLoS ONE, 2015
Colletotrichum lentis is a fungal pathogen of lentil in Canada but rarely reported elsewhere. Two races, Ct0 and Ct1, have been identified using differential lines. Our objective was to develop a PCR-probe differentiating these races.
Jonathan Durkin   +4 more
doaj   +1 more source

Variation of serine-aspartate repeats in membrane proteins possibly contributes to staphylococcal microevolution. [PDF]

open access: yesPLoS ONE, 2012
Tandem repeats (either as microsatellites or minisatellites) in eukaryotic and prokaryotic organisms are mutation-prone DNA. While minisatellites in prokaryotic genomes are underrepresented, the cell surface adhesins of bacteria often contain the ...
Jing Cheng, Huping Xue, Xin Zhao
doaj   +1 more source

The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo. [PDF]

open access: yesPLoS Genetics, 2009
In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in these processes is still poorly understood.
Cyril Ribeyre   +7 more
doaj   +1 more source

Fragile sites, chromosomal lesions, tandem repeats, and disease

open access: yesFrontiers in Genetics, 2022
Expanded tandem repeat DNAs are associated with various unusual chromosomal lesions, despiralizations, multi-branched inter-chromosomal associations, and fragile sites.
Mila Mirceta   +7 more
doaj   +1 more source

Molecular mining of alleles in water buffalo Bubalus bubalis and characterization of the TSPY1 and COL6A1 genes. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Minisatellites are an integral part of eukaryotic genomes and show variation in the complexity of their organization. Besides their presence in non-coding regions, a small fraction of them are part of the transcriptome, possibly participating
Sudeep Kumar   +3 more
doaj   +1 more source

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