Results 21 to 30 of about 36,419 (163)

MiR-210 promotes bone formation in ovariectomized rats by regulating osteogenic/adipogenic differentiation of bone marrow mesenchymal stem cells through downregulation of EPHA2 [PDF]

Journal of Orthopaedic Surgery and Research, 2023
Purpose In osteoporosis, the balance between osteogenic and adipogenic differentiation of mesenchymal stem cells (MSCs) is disrupted. The osteogenic differentiation of bone marrow MSCs (BMSCs) is important for improving osteoporosis.
Lijue Ren, Xiaohui Zhu, Jiuting Tan, Xiangyu Lv, Jiahui Wang, Fei Hua   +5 more
doaj   +2 more sources

Diagnostic Value of Plasma miR-181b, miR-196a, and miR-210 Combination in Pancreatic Cancer

Gastroenterology Research and Practice, 2020
Purpose. This study was aimed at investigating the roles of plasma miR-181b, miR-196a, and miR-210 in the diagnosis of pancreatic cancer (PC). Methods. Plasma samples were isolated from 40 patients with PC and 40 healthy individuals, respectively.
Gongpan Liu, Cunhua Shao, Anyun Li, Xiaobin Zhang, Xingjun Guo, Jiangong Li   +5 more
doaj   +1 more source

MicroRNA-210 regulates dendritic morphology and behavioural flexibility in mice [PDF]

, 2023
MicroRNAs are known to be critical regulators of neuronal plasticity. The highly-conserved, hypoxia- regulated microRNA-210 (miR-210) has been shown to be associated with long term memory in invertebrates and dysregulated in neurodevelopmental and ...
Claudianos, Charles, Lu, Jing, Nithianantharajah, Jess, Watts, Michelle, Williams, Gabrielle   +4 more
core   +1 more source

Long Non-coding RNA DLEU2L Targets miR-210-3p to Suppress Gemcitabine Resistance in Pancreatic Cancer Cells via BRCA2 Regulation

Frontiers in Molecular Biosciences, 2021
Gemcitabine (GEM) resistance remains a challenging clinical issue to overcome in chemotherapy against pancreatic cancer. We previously demonstrated that miR-210 derived from pancreatic cancer stem cells enhanced the GEM-resistant properties of pancreatic
Fei Xu, Heshui Wu, Jiongxin Xiong, Tao Peng   +3 more
doaj   +1 more source

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma [PDF]

, 2017
The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Carbone, Antonio, Costantini, Manuela, DI CARLO, Angelina, Fazi, Francesco, Gallucci, Michele, Marigliano, Chiara, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Ricci, Serena, Simone, Giuseppe, Tito, Claudia   +12 more
core   +2 more sources

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

Cell Death and Disease, 2021
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that miR ...
Zaccagnini Germana, Greco Simona, Longo Marialucia, Maimone Biagina, Voellenkle Christine, Fuschi Paola, Carrara Matteo, Creo Pasquale, Maselli Davide, Tirone Mario, Mazzone Massimiliano, Gaetano Carlo, Spinetti Gaia, Martelli Fabio   +13 more
doaj   +1 more source

Inhibition of microRNA-210 provides neuroprotection in hypoxic–ischemic brain injury in neonatal rats

Neurobiology of Disease, 2016
Perinatal hypoxic–ischemic encephalopathy (HIE) is associated with high neonatal mortality and severe long-term neurologic morbidity. Yet the mechanisms of brain injury in infants with HIE remain largely elusive.
Qingyi Ma, Chiranjib Dasgupta, Yong Li, Nikita M. Bajwa, Fuxia Xiong, Benjamin Harding, Richard Hartman, Lubo Zhang   +7 more
doaj   +1 more source

Analysis of differential expression of hypoxia-inducible microRNA-210 gene targets in mild and severe preeclamptic patients

Non-coding RNA Research, 2021
Preeclampsia (PE) is a multi-system disorder that is specific to human pregnancy. Inadequate oxygenation of uterus and placenta is considered as one of the leading causes for the disease.
Deeba S. Jairajpuri, Zainab H. Malalla, Sameh Sarray, Naeema Mahmood   +3 more
doaj   +1 more source

miR-210: More than a silent player in hypoxi [PDF]

, 2011
Multiple studies have consistently established that miR (microRNA)-210 induction is a feature of the hypoxic response in both normal and transformed cells.
Devlin, Cecilia, Greco, Simona, Ivan, Mircea, Martelli, Fabio   +3 more
core   +1 more source

Dysregulation of miR-210 is involved in the development of diabetic retinopathy and serves a regulatory role in retinal vascular endothelial cell proliferation

European Journal of Medical Research, 2020
Background Diabetic retinopathy is a common complication of diabetes mellitus (DM). The purpose of this study was to investigate the expression and clinical significance of miR-210 in DR patients and explore the regulatory effect of miR-210 on vascular ...
Chengyu Yin, Xiangqiang Lin, Yafei Sun, Xinli Ji   +3 more
doaj   +1 more source