Results 41 to 50 of about 36,419 (163)

Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma [PDF]

open access: yes, 2017
The majority of lung cancer deaths are caused by metastatic disease. MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression and miRNA dysregulation can contribute to metastatic progression. Here, small RNA sequencing was used to profile
Daugaard, Iben   +7 more
core   +2 more sources

miR-210 controls the evening phase of circadian locomotor rhythms through repression of Fasciclin 2.

open access: yesPLoS Genetics, 2019
Circadian clocks control the timing of animal behavioral and physiological rhythms. Fruit flies anticipate daily environmental changes and exhibit two peaks of locomotor activity around dawn and dusk.
Ye Niu   +4 more
doaj   +1 more source

TLR3-induced placental miR-210 down-regulates the STAT6/interleukin-4 pathway. [PDF]

open access: yesPLoS ONE, 2013
Several clinical studies have reported increased placental miR-210 expression in women with PE compared to normotensive women, but whether miR-210 plays a role in the etiology of PE is unknown.
Shelley E Kopriva   +3 more
doaj   +1 more source

Over-expression of miR-210 inhibits H2O2-induced adipogenic differentiation of rat BM-MSCs [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate the effect of miR-210 on hydrogen peroxide (H2O2)-induced adipogenic differentiation of rat bone marrow mesenchymal stem cells (BM-MSCs). Methods The SD rat BM-MSCs were isolated, cultured and identified.
FENG Baohong, YU Yean, YAN Li, WU Jun, ZHANG Yanxia, ZHU Geli
doaj   +1 more source

microRNA. Diagnostic Perspective [PDF]

open access: yes, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

open access: yes, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria   +6 more
core   +1 more source

Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells. [PDF]

open access: yesPLoS ONE, 2018
MicroRNA-210 (miR-210) is a robust target for hypoxia-inducible factor, and its overexpression has been detected in a variety of solid tumors. However, the role of miR-210 in the development, progression and response to therapy in cholangiocarcinoma (CCA)
Runglawan Silakit   +11 more
doaj   +1 more source

SWIM: A computational tool to unveiling crucial nodes in complex biological networks [PDF]

open access: yes, 2017
SWItchMiner (SWIM) is a wizard-like software implementation of a procedure, previously described, able to extract information contained in complex networks.
Colombo, Teresa   +5 more
core   +2 more sources

Clinical Significance of miR-210 and its Prospective Signaling Pathways in Non-Small Cell Lung Cancer: Evidence from Gene Expression Omnibus and the Cancer Genome Atlas Data Mining with 2763 Samples and Validation via Real-Time Quantitative PCR

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Since the function of microRNA (miR)-210 in non-small cell lung cancer (NSCLC) remains unclear, we aimed to explore the clinical significance of miR-210 in NSCLC.
Rong-quan He   +8 more
doaj   +1 more source

Malignancy Associated MicroRNA Expression Changes in Canine Mammary Cancer of Different Malignancies [PDF]

open access: yes, 2014
MicroRNA has been suspected to be generally involved in carcinogenesis since their first description. A first study supported this assumption for canine mammary tumors when miRNA expression was compared to normal gland.
Deetzen, Marie-Charlotte   +3 more
core   +3 more sources

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