Results 61 to 70 of about 39,772 (266)

Over-expression of miR-210 inhibits H2O2-induced adipogenic differentiation of rat BM-MSCs [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate the effect of miR-210 on hydrogen peroxide (H2O2)-induced adipogenic differentiation of rat bone marrow mesenchymal stem cells (BM-MSCs). Methods The SD rat BM-MSCs were isolated, cultured and identified.
FENG Baohong, YU Yean, YAN Li, WU Jun, ZHANG Yanxia, ZHU Geli
doaj   +1 more source

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

open access: yes, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria   +6 more
core   +1 more source

microRNA. Diagnostic Perspective [PDF]

open access: yes, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

Clinical Significance of miR-210 and its Prospective Signaling Pathways in Non-Small Cell Lung Cancer: Evidence from Gene Expression Omnibus and the Cancer Genome Atlas Data Mining with 2763 Samples and Validation via Real-Time Quantitative PCR

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Since the function of microRNA (miR)-210 in non-small cell lung cancer (NSCLC) remains unclear, we aimed to explore the clinical significance of miR-210 in NSCLC.
Rong-quan He   +8 more
doaj   +1 more source

miRNAs link metabolic reprogramming to oncogenesis [PDF]

open access: yes, 2013
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditions. This alternative metabolic circuitry is sufficient to support the biosynthetic and energy requirements for cancer ...
Hatziapostolou, M   +2 more
core   +1 more source

Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma [PDF]

open access: yes, 2017
The majority of lung cancer deaths are caused by metastatic disease. MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression and miRNA dysregulation can contribute to metastatic progression. Here, small RNA sequencing was used to profile
Daugaard, Iben   +7 more
core   +2 more sources

Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo

open access: yesMolecular Therapy: Nucleic Acids, 2018
We previously found that 19 microRNAs (miRNAs) significantly increased in the sera of hepatocellular carcinoma (HCC) patients. Here, we evaluated whether these miRNAs were secreted by HCC cells and contributed to tumor angiogenesis. High level of miR-210-
Xue-Jia Lin   +6 more
doaj   +1 more source

Gingerol ameliorates neuronal damage induced by hypoxia‐reoxygenation via the miR‐210/brain‐derived neurotrophic factor axis

open access: yesKaohsiung Journal of Medical Sciences, 2022
The specific mechanism of gingerol in cerebral ischemia remains unknown. A neuroprotective function for miR‐210 in cerebral ischemia has been identified.
Yang Zhai   +7 more
doaj   +1 more source

miR-210-3p protects against osteoarthritis through inhibiting subchondral angiogenesis by targeting the expression of TGFBR1 and ID4

open access: yesFrontiers in Immunology, 2022
Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it alters the balance of subchondral bone remodeling and causes progressive cartilage degradation.
Han Tang   +6 more
doaj   +1 more source

Radiogenomics in clear cell renal cell carcinoma: correlations between advanced CT imaging (texture analysis) and microRNAs expression [PDF]

open access: yes, 2019
Purpose: A relevant challenge for the improvement of clear cell renal cell carcinoma management could derive from the identification of novel molecular biomarkers that could greatly improve the diagnosis, prognosis, and treatment choice of these ...
Badia, S.   +12 more
core   +1 more source

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