miR-210 Mediated Hypoxic Responses in Pancreatic Ductal Adenocarcinoma. [PDF]
ACS OmegaPancreatic ductal adenocarcinoma (PDAC) is one among the most lethal malignancies due to its aggressive behavior and resistance to conventional therapies.
Mortoglou M +4 more
europepmc +7 more sources
Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer. [PDF]
Curr Issues Mol Biol, 2023 Pancreatic cancer (PC) poses significant clinical challenges, with late-stage diagnosis and limited therapeutic options contributing to its dismal prognosis.
Lian M, Mortoglou M, Uysal-Onganer P.
europepmc +5 more sources
MiR-210 regulates lung adenocarcinoma by targeting HIF-1α [PDF]
Heliyon, 2023 Object: This study sought to elucidate the role of microRNA-210 (miR-210) in the occurrence and development of lung adenocarcinoma (LUAD). Methods: The levels of lncRNA miR-210HG and miR-210 in LUAD tissues and corresponding normal tissues were analyzed ...
Guolei Cao +6 more
doaj +4 more sources
Hypoxia‐induced miR‐210‐3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2 mediated monocyte infiltration [PDF]
Molecular Oncology, 2022 In most cancers, tumor hypoxia downregulates the expression of C‐C motif chemokine 2 (CCL2), and this downregulation has been implicated in monocyte infiltration and tumor progression; however, the molecular mechanism is not yet clear.
Leena Arora +8 more
doaj +3 more sources
Exercise-Induced miR-210 Promotes Cardiomyocyte Proliferation and Survival and Mediates Exercise-Induced Cardiac Protection against Ischemia/Reperfusion Injury [PDF]
ResearchExercise can stimulate physiological cardiac growth and provide cardioprotection effect in ischemia/reperfusion (I/R) injury. MiR-210 is regulated in the adaptation process induced by exercise; however, its impact on exercise-induced physiological ...
Yihua Bei +18 more
doaj +3 more sources
miR-210 in ischaemic stroke: biomarker potential, challenges and future perspectives. [PDF]
Eur J Med ResIschaemic stroke, a leading cause of global morbidity and mortality, necessitates effective biomarkers for enhanced diagnostic and prognostic stratification.
Aderinto N +11 more
europepmc +5 more sources
Elevation of Circulating miR-210 Participates in the Occurrence and Development of Type 2 Diabetes Mellitus and Its Complications [PDF]
Journal of Diabetes Research, 2022 Objective. Circulating miRNAs are acclaimed biomarkers to predict the occurrence and progression of type 2 diabetes mellitus (T2DM). This study is aimed at analyzing the correlation of circulating miR-210 level and obesity-associated T2DM and then ...
Xi Chen +4 more
doaj +3 more sources
miR-210-3p protects against osteoarthritis through inhibiting subchondral angiogenesis by targeting the expression of TGFBR1 and ID4 [PDF]
Frontiers in Immunology, 2022 Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it alters the balance of subchondral bone remodeling and causes progressive cartilage degradation.
Han Tang +6 more
doaj +3 more sources
MiR-210 improves postmenopausal osteoporosis in ovariectomized rats through activating VEGF/Notch signaling pathway. [PDF]
BMC Musculoskelet Disord, 2023 Background To explore the effect and mechanism of action of miR-210 on postmenopausal osteoporosis (PMPO) in ovariectomized rats in vivo. Methods An ovariectomized (OVX) rat model was established by ovariectomy.
Ren LJ, Zhu XH, Tan JT, Lv XY, Liu Y.
europepmc +2 more sources
miR-210-3p enriched extracellular vesicles from hypoxic neuroblastoma cells stimulate migration and invasion of target cells. [PDF]
Cell Biosci, 2023 Background Tumor hypoxia stimulates release of extracellular vesicles (EVs) that facilitate short- and long-range intercellular communication and metastatization. Albeit hypoxia and EVs release are known features of Neuroblastoma (NB), a metastasis-prone
Fusco P +9 more
europepmc +2 more sources