Results 31 to 40 of about 15,193 (187)

Serum miR-210-3p can be used to differentiate between patients with pancreatic ductal adenocarcinoma and chronic pancreatitis. [PDF]

Biomed Rep, 2021
Patients with chronic pancreatitis (CP) are at risk of developing pancreatic ductal adenocarcinoma (PDAC). To the best of our knowledge, there are no suitable non-invasive biomarkers for differentiation between CP and PDAC; however, potential molecular candidates include circulating miRNAs due to ease of extraction, their stability and tissue ...
Guz M, Jeleniewicz W, Cybulski M, Kozicka J, Kurzepa J, Mądro A.   +5 more
europepmc   +5 more sources

MiR-210-3p attenuates lipid accumulation and inflammation in atherosclerosis by repressing IGF2 [PDF]

Bioscience, Biotechnology, and Biochemistry, 2020
ABSTRACT Previous studies have shown that miR-210-3p is involved in the development and progression of atherosclerosis, but its specific mechanisms are still unclear. This study aims to reveal the mechanism of miR-210-3p and its target genes in macrophage lipid deposition and inflammatory response, and provide new ideas for the treatment
Xiang-Rui, Qiao, Liang, Wang, Mengping, Liu, Yuling, Tian, Tao, Chen   +4 more
openaire   +2 more sources

Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect. [PDF]

Exp Biol Med (Maywood), 2021
Hypoxia, the most common feature in the tumor microenvironment, is closely related to tumor malignant progression and poor patient’s prognosis. Exosomes, initially recognized as cellular “garbage dumpsters”, are now known to be important mediums for mediating cellular communication in tumor microenvironment.
Ge L, Zhou F, Nie J, Wang X, Zhao Q.
europepmc   +3 more sources

Mesenchymal stem cell‑derived extracellular vesicles prevent neural stem cell hypoxia injury via promoting miR‑210‑3p expression. [PDF]

Mol Med Rep, 2020
Neural stem cells (NSCs) have the potential to give rise to offspring cells and hypoxic injury can impair the function of NSCs. The present study investigated the effects of mesenchymal stem cell (MSC)‑derived extracellular vesicles (EVs) on NSC injury, as well as the underlying mechanisms.
Li F, Zhang J, Liao R, Duan Y, Tao L, Xu Y, Chen A.   +6 more
europepmc   +4 more sources

OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway. [PDF]

Biomed Res Int, 2020
This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the angiogenesis of HUVECs through miR‐210‐3p expression and exploring the relationship among miR‐210‐3p, its target protein, and the possible mechanism of angiogenesis regulation.
Wang H, Wang L, Zhou X, Luo X, Liu K, Jiang E, Chen Y, Shao Z, Shang Z.   +8 more
europepmc   +4 more sources

MiR-210-3p protects endometriotic cells from oxidative stress-induced cell cycle arrest by targeting BARD1. [PDF]

Cell Death Dis, 2019
AbstractEndometriosis is associated with benign but adversely developed cysts in the extrauterine environment. The oxidative imbalanced environment induces DNA damage and affects cell cycle progression of endometrial stromal cells (ESCs) and endometrial epithelial cells, but how endometriotic cells maintain proliferation in the presence of oxidative ...
Dai Y, Lin X, Xu W, Lin X, Huang Q, Shi L, Pan Y, Zhang Y, Zhu Y, Li C, Liu L, Zhang S.   +11 more
europepmc   +4 more sources

Long non-coding RNA PAXIP-AS1 promotes viability, invasion, and migration of HTR-8/SVneo cells through miR-210-3p/BDNF axis

Hypertension in Pregnancy, 2022
Objective The aim of this research was to explore the role and potential mechanism of long non-coding RNA PAXIP-AS1 in preeclampsia. Methods To investigate the effects of PAXIP-AS1 on cell viability, migration, and invasion.
Xuejuan Chen, Xiang Kong, Gang Niu, Fengjin Qin, Yan Duan, Fengjiao Ren   +5 more
doaj   +1 more source

MicroRNA-210-3p is transcriptionally upregulated by hypoxia induction and thus promoting EMT and chemoresistance in glioma cells.

PLoS ONE, 2021
BackgroundGlioma is the most common and lethal form of brain cancer. It is highly malignant and is often characterized by chemoresistance and radioresistance, which are thought to mainly result from hypoxic microenvironments. Various tumour-promoting and
Hong Liu, Changjin Chen, Jinhao Zeng, Ziyi Zhao, Qiongying Hu   +4 more
doaj   +1 more source

miR-33a-5p in small extracellular vesicles as non-invasive biomarker for oxaliplatin sensitivity in human colorectal cancer cells

Biochemistry and Biophysics Reports, 2021
microRNAs (miRNAs) contained in small extracellular vesicles (sEVs) are candidates for non-invasive biomarkers. Oxaliplatin (L-OHP) has been approved for advanced colorectal cancer (CRC) chemotherapy.
Shota Tanaka, Mika Hosokawa, Takumi Miyamoto, Aiko Nakagawa, Mika Haruna, Kumiko Ueda, Seigo Iwakawa, Ken-ichi Ogawara   +7 more
doaj   +1 more source

A pilot study reveals the potential of miR-31-3p and miR-196a-5p as non-invasive biomarkers in advanced laryngeal cancer [PDF]

Folia Medica, 2021
Introduction: Recently, miRNAs have become popular molecules used as non-invasive biomarkers in cancer diseases.Aim: The aim of the study was to explore the expression of four miRNAs isoforms: miR-31-3p, miR-196a-5p, miR-210-3p and miR-424-5p in plasma ...
Silva Garo Kyurkchiyan, Todor Miroslavov Popov, Felitsiya Shakola, Julian Rangachev, Vanyo Ivanov Mitev, Radka Kaneva   +5 more
doaj   +3 more sources