Results 61 to 70 of about 15,720 (202)

A pilot study identifying a set of microRNAs as precise diagnostic biomarkers of acute kidney injury [PDF]

, 2015
In the last decade, Acute Kidney Injury (AKI) diagnosis and therapy have not notably improved probably due to delay in the diagnosis, among other issues. Precocity and accuracy should be critical parameters in novel AKI biomarker discovery. microRNAs are
Aguado-Fraile, E., Candela, Á., Conde, E., García-Bermejo, M.L., Liaño, F., Lietor, A., Martín-Gómez, L., Ponte, B., Ramos, E., Rodríguez, M.   +9 more
core   +4 more sources

Discovery and Validation of Circulating Hsa-miR-210-3p as a Potential Biomarker for Primary Open-Angle Glaucoma

Investigative Opthalmology & Visual Science, 2019
Blood-based examination tools for glaucoma diagnosis in clinical practice, which can be useful for screening patients when traditional ophthalmic examinations cannot be utilized, are not available thus far. This study aimed to identify circulating microRNAs (miRNAs) associated with primary open-angle glaucoma (POAG) and explore their utility as ...
Yaoming, Liu, Yayi, Wang, Yang, Chen, Xiuli, Fang, Tao, Wen, Mianli, Xiao, Shida, Chen, Xiulan, Zhang   +7 more
openaire   +2 more sources

Downregulation of miR-210-3p Attenuates High Glucose-Induced Angiogenesis of Vascular Endothelial Cells via Targeting FGFRL1

Ophthalmic Research, 2023
Introduction: Vascular endothelial cell injury and angiogenesis induced by hyperglycemia are the main pathological basis of vascular complications in diabetes mellitus. Our study aimed to investigate the role and mechanism of miR-210-3p in high glucose (HG)-induced angiogenesis. Methods: Human umbilical vein endothelial cells (HUVECs) were treated with
Tao, Wen, Yiwen, Hong, Yamei, Cui, Jianying, Pan, Yishen, Wang, Yan, Luo   +5 more
openaire   +2 more sources

Characterization of microRNA Levels in Synovial Fluid from Knee Osteoarthritis and Anterior Cruciate Ligament Tears

Biomedicines, 2022
This study investigated modifications of microRNA expression profiles in knee synovial fluid of patients with osteoarthritis (OA) and rupture of the anterior cruciate ligament (ACL).
Laura Rizzi, Marco Turati, Elena Bresciani, Filippo Maria Anghilieri, Ramona Meanti, Laura Molteni, Massimiliano Piatti, Nicolò Zanchi, Silvia Coco, Francesco Buonanotte, Luca Rigamonti, Giovanni Zatti, Vittorio Locatelli, Robert J. Omeljaniuk, Marco Bigoni, Antonio Torsello   +15 more
doaj   +1 more source

Electroacupuncture reduces scopolamine-induced amnesia via mediating the miR-210/SIN3A and miR-183/SIN3A signaling pathway

Molecular Medicine, 2020
Background The expression of SIN3A is closely correlated with electroacupuncture (EA) treatment efficacy of scopolamine-induced amnesia (SIA), but its underlying mechanisms remain to be further explored.
Fan Ye, Shiming Tian, Huimin Hu, Zhengwen Yu   +3 more
doaj   +1 more source

Expression profile of plasma microRNAs and target genes in patients with complicated pregnancy

Акушерство, гинекология и репродукция, 2023
Aim: comparative analysis of the expression profile of plasma microRNAs and target genes in patients with complicated pregnancy.Materials and Methods. A prospective observational comparative study in parallel groups was carried out. The study included 73
D. G. Pashkovsky, E. V. Solovieva, Ts. R. Rabadanova, P. T. Gorbunova, A. B. Dubovaya, E. R. Muslimova, E. E. Khoroz, Z. S. Karabash, L. E. Sorokina   +8 more
doaj   +1 more source

Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model [PDF]

, 2016
MicroRNAs (miRNAs) are small non-coding RNAs that play an important role in the post-transcriptional regulation of gene expression. miRNAs are involved in the regulation of many biological processes such as differentiation, apoptosis, and cell ...
Elena Chiavacci, Francesco Russo, Francesco Russo, Giuseppe Rainaldi, Ivan Arisi, Letizia Pitto, Mara D'Onofrio, Marco Groth, Marco Pellegrini, Mario Baumgart, Romina D'Aurizio   +10 more
core   +2 more sources

Auto‐Generated Valence States in Electrocatalysts for Boosting Oxygen and Hydrogen Evolution Kinetics in Alkaline Water/Alkaline Seawater/Simulated Seawater/Natural Seawater

Advanced Functional Materials, EarlyView.
This review systematically highlights the latest achievements in mixed‐valence states relevant to hydrogen and oxygen evolution reactions, providing essential insights into future directions and methods for large‐scale practical implementation. This critical review is expected to provide an overview of recent advancements in diverse valence‐state metal
Jitendra N. Tiwari, Gokul Bhaskaran, Krishan Kumar, Yun Suk Huh, Young‐Kyu Han   +4 more
wiley   +1 more source

MiR-210-3p Enhances Cardiomyocyte Apoptosis and Mitochondrial Dysfunction by Targeting the NDUFA4 Gene in Sepsis-Induced Myocardial Dysfunction

International Heart Journal, 2021
Sepsis-induced myocardial dysfunction (SIMD) is a common complication with high incidence rates in sepsis patients. This study aimed to investigate the roles of miR-210-3p in regulating cardiomyocyte apoptosis and mitochondrial dysfunction associated with SIMD pathogenesis.A rat sepsis model was established by cecal ligation and puncture.
Dandan, Chen, Yu, Hou, Xingjun, Cai
openaire   +3 more sources

Plasma micrornas as a biomarker for detection of colorectal cancer in Hospital Universiti Sains Malaysia [PDF]

, 2023
Colorectal cancer (CRC) is one of the cancer with a low survival rate and usually end with death. Colonoscopy is currently the gold standard in detecting CRC disease. However, due to the inconvenience of the procedure, it becomes less appealing. Since
Mohamed, Syarah Syamimi
core