Results 21 to 30 of about 4,858 (119)

The influence of concentration of micro-rna hsa-mir-370-3p and CYP2D6*4 on equilibrium concentration of mirtazapine in patients with major depressive disorder [PDF]

European Psychiatry, 2021
Introduction Mirtazapine is commonly prescribed to patients diagnosed with major depressive disorder.Some proportion of these patients do not show adequate response to treatment regimen containing mirtazapine, whereas many of them experience dose ...
M. Zastrozhin, V. Skryabin, D. Sychev, E. Bryun   +3 more
doaj   +2 more sources

Transcriptomic analysis revealed that oar-miR-370-3p was involved in the regulation of wool fineness in Ordos fine-wool sheep [PDF]

Frontiers in Veterinary Science
MicroRNA (miRNA) is a prominent topic in biological research, as it plays a crucial role in regulating various physiological processes. Identifying miRNAs associated with fiber traits enhances our understanding of the complex biological mechanisms ...
Cuiling Wu, Gvlnigar Amar, Asma Anwar, Wenna Liu, Sen Tang, Shengchao Ma, Shengchao Ma, Xuefeng Fu   +7 more
doaj   +2 more sources

Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway. [PDF]

Int J Biol Sci, 2022
Increasing evidence suggests that circular RNAs (circRNAs) are involved in regulating tumor biological activity. Glioblastoma (GBM) is one of the most lethal diseases characterized by highly aggressive proliferative and invasive behaviors. We aimed to explore how circRNAs influenced GBM biological activity.
Li B, Chen J, Wu Y, Luo H, Ke Y.
europepmc   +3 more sources

circITGA7 Acts as a miR-370-3p Sponge to Suppress the Proliferation of Prostate Cancer. [PDF]

J Oncol, 2021
Abstract Objective: Prostate cancer (PCa) refers to one of the most common tumors in male’s genitourinary system. Emerging research has confirmed that circRNAs play an important role in the occurrence and development of tumors. However, the correlation between circular RNA circITGA7 and PCa still remains unclear.
Luo G, Li G, Wan Z, Zhang Y, Liu D, Guo Y.   +5 more
europepmc   +4 more sources

Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats. [PDF]

G3 (Bethesda), 2021
Abstract MicroRNAs (miRNAs), a class of 22 nucleotide (nt) noncoding RNAs, negatively regulate mRNA posttranscriptional modification in various biological processes. Morphogenesis of skin hair follicles in cashmere goats is a dynamic process involving many key signaling molecules, but the associated cellular biological mechanisms induced
Hai E, Han W, Wu Z, Ma R, Shang F, Wang M, Liang L, Rong Y, Pan J, Wang Z, Wang R, Su R, Zhao Y, Liu Z, Wang Z, Li J, Zhang Y.   +16 more
europepmc   +5 more sources

lncRNA SNHG15 Promotes Ovarian Cancer Progression through Regulated CDK6 via Sponging miR-370-3p. [PDF]

Biomed Res Int, 2021
Ovarian cancer is a kind of cancer from the female genital tract; the molecular mechanism still needs to be explored. lncRNA plays a vital role in tumorigenesis and development. Our aim was to identify oncogenic lncRNAs in ovarian cancer and explore the potential molecular mechanism.
Wang Y, Ding M, Yuan X, Jiao R, Zhu D, Huang W, Deng W, Liu Y.   +7 more
europepmc   +3 more sources

Inhibition of intervertebral disc disease progression via the circPKNOX1-miR-370-3p-KIAA0355 axis. [PDF]

Cell Death Discov, 2021
AbstractThe molecular mechanism underlying the development of intervertebral disc disease (IVDD) is not completely understood. Circular RNAs (circRNAs) play a significant role in the occurrence and development of various diseases, and studies have shown that circPKNOX1 is involved in the compensatory response of extracellular matrix synthesis and ...
Huang Y, Gao J, Wang J, Ye H, Yao T, Xu Y, Chen Z, Shen S, Ma J.   +8 more
europepmc   +5 more sources

circ_0023461 Silencing Protects Cardiomyocytes from Hypoxia-Induced Dysfunction through Targeting miR-370-3p/PDE4D Signaling. [PDF]

Oxid Med Cell Longev, 2021
Background. Acute myocardial infarction (AMI) is a common cardiovascular disease with high disability and mortality. Circular RNAs (circRNAs) are implicated in the pathomechanism of multiple human diseases, including AMI. This study intended to explore the function and working mechanism of a novel circRNA circ_0023461 in hypoxia‐induced cardiomyocytes.
Ren K, Li B, Jiang L, Liu Z, Wu F, Zhang Y, Liu J, Duan W.   +7 more
europepmc   +4 more sources

Circ_0010729 knockdown protects cardiomyocytes against hypoxic dysfunction via miR-370-3p/TRAF6 axis. [PDF]

EXCLI J, 2020
EXCLI Journal; 19:Doc1520; ISSN 1611 ...
Zhang J, Gao C, Zhang J, Ye F.
europepmc   +4 more sources

Silencing miR-370-3p rescues funny current and sinus node function in heart failure. [PDF]

Sci Rep, 2020
AbstractBradyarrhythmias are an important cause of mortality in heart failure and previous studies indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel HCN4 in this process. Here we show that, in a mouse model of heart failure in which there is sinus bradycardia, there is upregulation of a microRNA (miR-370-3p ...
Yanni J, D'Souza A, Wang Y, Li N, Hansen BJ, Zakharkin SO, Smith M, Hayward C, Whitson BA, Mohler PJ, Janssen PML, Zeef L, Choudhury M, Zi M, Cai X, Logantha SJRJ, Nakao S, Atkinson A, Petkova M, Doris U, Ariyaratnam J, Cartwright EJ, Griffiths-Jones S, Hart G, Fedorov VV, Oceandy D, Dobrzynski H, Boyett MR.   +27 more
europepmc   +8 more sources