Results 51 to 60 of about 4,858 (119)

Long noncoding RNA FGF14-AS2 inhibits breast cancer metastasis by regulating the miR-370-3p/FGF14 axis. [PDF]

open access: yesCell Death Discov, 2020
AbstractLong noncoding RNAs (lncRNAs) have emerged as important regulators in cancers, including breast cancer. However, the overall biological roles and clinical significance of most lncRNAs are not fully understood. This study aimed to elucidate the potential role of a novel lncRNA FGF14-AS2 and the mechanisms underlying metastasis in breast cancer ...
Jin Y   +11 more
europepmc   +4 more sources

Dynamic changes of miRNAs in skeletal muscle development at New Zealand rabbits

open access: yesBMC Genomics, 2021
Background miRNA is one of the crucial roles in the complex and dynamic network that regulates the development of skeletal muscle. The landscape of skeletal muscle miRNAs from fetus to adult in New Zealand rabbits has not been revealed yet.
Jing Jing   +10 more
doaj   +1 more source

An Insight into the microRNAs Associated with Arteriovenous and Cavernous Malformations of the Brain

open access: yesCells, 2021
Background: Brain arteriovenous malformations (BAVMs) and cerebral cavernous malformations (CCMs) are rare developmental anomalies of the intracranial vasculature, with an irregular tendency to rupture, and as of yet incompletely deciphered ...
Ioan Alexandru Florian   +6 more
doaj   +1 more source

Electrocatalytic Reduction of CO2 to Ethylene: Catalyst Design and Synchrotron‐Based Characterizations

open access: yesAdvanced Functional Materials, EarlyView.
This review evaluates strategies for electrochemical CO2 reduction to ethylene, focusing on copper‐based catalyst design and microenvironment modulation to achieve industrial‐grade performance. By leveraging operando synchrotron‐based characterizations, we provide a multiscale understanding of dynamic structural transformations and key reaction ...
Meng Zhang, Zuolong Chen, Yimin A. Wu
wiley   +1 more source

Recent Advances in Nano‐Microstructured Catalysts for Electrochemical Seawater Electrocatalysis

open access: yesAdvanced Energy Materials, EarlyView.
This review highlights advances in nano‐ and microstructured catalysts for electrochemical seawater conversion. It elucidates design principles, mechanistic understanding, and machine‐learning‐assisted discovery, and outlines key challenges and future opportunities toward efficient, selective, and durable seawater electrocatalysis.
Xiaodong Shao   +5 more
wiley   +1 more source

LINC01232 Sponges Multiple miRNAs and Its Clinical Significance in Pancreatic Adenocarcinoma Diagnosis and Prognosis

open access: yesTechnology in Cancer Research & Treatment, 2021
Background: Long noncoding RNAs have been demonstrated to play important roles in different kinds of human malignancy. The purpose of this study was to evaluate the diagnostic and prognostic value of long intergenic non-protein coding RNA 1232 (LINC01232)
Wenyan Du MM   +4 more
doaj   +1 more source

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang   +4 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features

open access: yesWorld Journal of Surgical Oncology, 2012
Background MicroRNA (miRNA) expression is known to be deregulated in ovarian carcinomas. However, limited data is available about the miRNA expression pattern for the benign or borderline ovarian tumors as well as differential miRNA expression pattern ...
Lee Heejeong   +8 more
doaj   +1 more source

Myc-mediated circular RNA circMcph1/miR-370-3p/Irak2 axis is a progressive regulator in hepatic fibrosis

open access: yesLife Sciences, 2023
Treating hepatic fibrosis (HF) is a major challenge worldwide. However, the biological functions and regulatory mechanisms of circular RNAs (circRNAs) remain unclear in HF. The present study aimed to elucidate the novel role of circMcph1 in HF.HF mouse model was established by injecting CCl4 intraperitoneally and validated using hematoxylin and eosin ...
Jin-Jin, Xu   +8 more
openaire   +2 more sources

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