Results 101 to 110 of about 47,292 (192)
MicroRNA-532-5p Regulates Pericyte Function by Targeting the Transcription Regulator BACH1 and Angiopoietin-1 [PDF]
MicroRNAs regulate endothelial function and angiogenesis, but their implication in pericyte biology remains undetermined. A PCR array, covering a panel of 379 human microRNAs, showed microRNA-532-5p to be one of the most differentially modulated by ...
Alvino, Valeria V. +10 more
core +3 more sources
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen +12 more
wiley +1 more source
The perfect crystal packing achieved via the halogen‐bond (XB) coupled halogenated‐π‐conjugation strategy effectively induces an ultrahigh birefringence (Δn = 0.97), which exhibits promising potential in polarization control and phase modulation.
Miao‐Bin Xu +6 more
wiley +1 more source
MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model.
BackgroundIschemic retinopathies (IRs) are leading causes of visual impairment. They are characterized by an initial phase of microvascular degeneration and a second phase of aberrant pre-retinal neovascularization (NV).
Michel Desjarlais +6 more
doaj +1 more source
Abstract RNA‐based therapeutics are emerging as a powerful platform for disease treatment, and one of the novel RNA molecules with therapeutic potential is circular RNA (circRNA). The ubiquitously expressed circRNAs are covalently closed, single‐stranded RNA molecules formed by backsplicing and are known to regulate gene expression by either sponging ...
Pragnya Das +3 more
wiley +1 more source
MicroRNA-532-3p Modulates Colorectal Cancer Cell Proliferation and Invasion via Suppression of FOXM1 [PDF]
Colorectal cancer (CRC) is a heterogeneous disease and classified into various subtypes, among which transcriptional alterations result in CRC progression, metastasis, and drug resistance.
Alahari, Suresh K. +4 more
core +2 more sources
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation [PDF]
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death. Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ancestry groups. To further define the
A Deshmukh +197 more
core +9 more sources
From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi +7 more
wiley +1 more source
High-throughput profiling for discovery of non-coding RNA biomarkers of lung disease. [PDF]
In respiratory medicine there is a need for clinical biomarkers for diagnosis, prognosis and assessment of response to therapy. Noncoding RNA (ncRNA) is expressed in all human cells; two major classes - long ncRNA and microRNA - are detectable ...
Greene, Catherine M, McKiernan, Paul J
core
A Comprehensive RNA Expression Signature for Cervical Squamous Cell Carcinoma Prognosis [PDF]
Clinicopathological characteristics alone are not enough to predict the survival of patients with cervical squamous cell carcinoma (CESC) due to clinical heterogeneity.
Jie Xiong +4 more
core +1 more source

