Results 71 to 80 of about 4,926 (186)

Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis

Frontiers in Molecular Neuroscience, 2018
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease. While genetics and other factors contribute to ALS pathogenesis, critical knowledge is still missing and validated biomarkers for monitoring the disease activity ...
Maria Liguori, Nicoletta Nuzziello, Alessandro Introna, Arianna Consiglio, Flavio Licciulli, Eustachio D’Errico, Antonio Scarafino, Eugenio Distaso, Isabella L. Simone   +8 more
doaj   +1 more source

Assessment Of Epsteın Barr Vırus Molecular Polymorphısm And Tumor Bıomarkers Assocıated Wıth Non- Hodgkın’s Lymphoma In Iraqı Patıents [PDF]

, 2022
The current study was conducted to evaluate the Epstein-Barr virus molecular polymorphism and tumor biomarkers associated with non-Hodgkin's lymphoma in Iraqi patients.
Aboomeıma, Wiqar Adnan Azeez
core  

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Differential Pattern of Circulating MicroRNA Expression in Patients with Intracranial Atherosclerosis

Biomedicines
Background: Intracranial atherosclerosis (ICAS) is a major cause of ischemic stroke, yet fundamental studies regarding epigenetic regulation of ICAS are lacking.
Marine M. Tanashyan, Anton A. Raskurazhev, Alla A. Shabalina, Andrey S. Mazur, Vladislav A. Annushkin, Polina I. Kuznetsova, Sergey N. Illarioshkin, Mikhail A. Piradov   +7 more
doaj   +1 more source

Dispersive Full‐Channel Jones Matrix Modulation in Elliptical Polarization Bases via a Single‐Layered Metasurface

Advanced Science, EarlyView.
This work presents a dispersive full‐channel Jones matrix modulation strategy using single‐layer metasurface. By synergizing wavelength dispersion engineering with elliptical polarization bases, independent control of four Jones matrix channels is achieved across multiple wavelengths.
Hairong He, Guangtao Cao, Shuhao Zhang, Hui Xu, Zhiquan Chen, Meiyu Peng, Yuting Jiang, Yueqiang Hu, Hui Jing, Huigao Duan, Hui Yang   +10 more
wiley   +1 more source

Relationship Between Coronary Atheroma, Epicardial Adipose Tissue Inflammation, and Adipocyte Differentiation Across the Human Myocardial Bridge

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin, Ingela Schnittger, Anna Nagy, Elizabeth Zanley, Yue Xu, Yanqiu Song, Koen Nieman, Jennifer A. Tremmel, Damini Dey, Jack Boyd, Harold Sacks   +10 more
doaj   +1 more source

Electrical pulse stimulation-induced tetanic exercise simulation increases the secretion of extracellular vesicles from C2C12 myotubes [PDF]

, 2023
Extracellular vesicles (EVs) released into the blood during exercise mediate its whole-body health effects. The differentiation of EVs released by skeletal muscle cells in vivo from those released by other cells is challenging, therefore, it is unclear ...
Akiyama, Hirokazu, Honda, Hiroyuki, Murata, Akari, Shimizu, Kazunori   +3 more
core   +1 more source

Basal Plane Activation of SnS2 Thin‐Film by Fluorine Doping for Selective Solar‐Driven CO2 Reduction With Enhanced Quantum Efficiency

Advanced Science, EarlyView.
The synergistic effect of fluorine doping and sulfur vacancies boosts the activity of the active sites without active‐site modulation, leading to enhanced CO2 photoreduction efficiency and a selectivity switch from CH4 to CO on tin disulfide continuous thin films. ABSTRACT Photocatalytic conversion of CO2 into value‐added fuels offers a viable approach
Tadios Tesfaye Mamo, Mohammad Qorbani, Adane Gebresilassie Hailemariam, Putikam Raghunath, Che‐Men Chu, Wen‐Hsin Yuan, Amr Sabbah, Yen‐Yu Wang, Shuo‐Yun Chang, Ming‐Chang Lin, Wei‐Yen Woon, Yu‐Jung Lu, Heng‐Liang Wu, Ken‐Tsung Wong, Kuei‐Hsien Chen, Li‐Chyong Chen   +15 more
wiley   +1 more source

Role of miRNA-mRNA Interaction in Neural Stem Cell Differentiation of Induced Pluripotent Stem Cells [PDF]

, 2020
miRNA regulates the expression of protein coding genes and plays a regulatory role in human development and disease. The human iPSCs and their differentiated progenies provide a unique opportunity to identify these miRNA-mediated regulatory mechanisms ...
Blangero, John, Curran, Joanne E., De Leon, Erica, Glahn, David C., Howard, Tom E., Kumar, Satish, Leandro, Ana C., Lehman, Donna M., Williams-Blangero, Sarah   +8 more
core   +2 more sources