CircPUM1 promotes cell growth and glycolysis in NSCLC via up-regulating METTL3 expression through miR-590-5p. [PDF]
Cell Cycle, 2021 RNA pumilio RNA binding family member 1 (circPUM1) has been reported to play important roles in the tumorigenesis of several cancers. However, the underlying molecular role of circPUM1 in non-small cell lung cancer (NSCLC) progression remains unknown. The qRT-PCR and western blot were used to evaluate the expression of RNAs and proteins.
Li M, Wang Q, Zhang X, Yan N, Li X.
europepmc +5 more sources
Coxsackievirus B infection induces the extracellular release of miR-590-5p, a proviral microRNA. [PDF]
Virology, 2019 Coxsackievirus B is a significant human pathogen and is a leading cause of myocarditis. We and others have observed that certain enteroviruses including coxsackievirus B cause infected cells to shed extracellular vesicles containing infectious virus. Recent reports have shown that vesicle-bound virus can infect more efficiently than free virus.
Germano JF +6 more
europepmc +4 more sources
Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto [PDF]
Jurnal Kesehatan Andalas, 2021 Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih +2 more
doaj +6 more sources
Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis. [PDF]
PLoS ONE, 2016 MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin +15 more
doaj +3 more sources
MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: MicroRNA (miRNA)-induced suppression of dendritic cells (DCs) has been implicated in many diseases. Therefore, accurate monitoring of miRNA endocytosis by DCs is important for understanding the role of miRNAs in many diseases.
Qiang Tong +7 more
doaj +3 more sources
Oncol Lett, 2021 Lung adenocarcinoma (LUAD) is the leading cause of cancer-related mortality worldwide. Long non-coding RNA (lncRNA) NUT family member 2A antisense RNA 1 (NUTM2A-AS1) is dysregulated in LUAD; however, its role in this disease remains unclear. The present study aimed to identify the underlying molecular mechanism of the effect of lncRNA NUTM2A-AS1 in ...
Wang J, Zha J, Wang X.
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Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes [PDF]
Cell Transplantation, 2020 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
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miR-590-5p regulates gastric cancer cell growth and chemosensitivity through RECK and the AKT/ERK pathway. [PDF]
Onco Targets Ther, 2016 The aim of this study was to determine the role of miRNA-590-5p in gastric cancer (GC) progression.Quantitative real-time polymerase chain reaction was performed to measure endogenous miR-590-5p levels in GC cells and tissues. Overexpression or knockdown of miR-590-5p in GC cells was performed by transfection with mimics or an inhibitor, respectively ...
Shen B +6 more
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Expression of serum microRNAs, mir-182-5p, and miR-590-3p and its clinical significance in neonatal sepsis [PDF]
Egyptian Pediatric Association GazetteBackground Neonatal sepsis is one of the life-threatening diseases. MicroRNAs are non-coding RNAs that play vital roles in various diseases. Methods This study included 50 neonates with sepsis and 60 healthy controls. RNA extraction and assessment of mir-
Soha M. Hamdy +4 more
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Circular RNA hsa_circ_0005114-miR-142-3p/miR-590-5p-adenomatous polyposis coli protein axis as a potential target for treatment of glioma. [PDF]
Oncol Lett, 2021 Wei B, Wang L, Zhao J.
europepmc +3 more sources