miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1 [PDF]
Analytical Cellular Pathology, 2022 Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Lin Shang +6 more
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Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer [PDF]
Frontiers in Molecular Biosciences, 2021 The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Guo-Dian Zheng +9 more
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miR-590–5p: A double-edged sword in the oncogenesis process
Cancer Treatment and Research Communications, 2022 Accumulating evidence suggests the critical role of miR-590–5p in various aspects of cellular homeostasis, including cancer. Furthermore, we and others have recently demonstrated that miRNA-590–5p acts as an oncogene in some cancers while it acts as a ...
Aklank Jain
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Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]
Discover OncologyObjective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu +4 more
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miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability [PDF]
Cancer Cell International, 2023 Background T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies.
Ying Liu +6 more
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Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p [PDF]
PPAR Research, 2019 Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is one of the major receptors expressed on the endothelium of arterial wall with a key role in endothelial dysfunction and the development of atherosclerosis.
Lei Xu +6 more
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miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expressionResearch in context [PDF]
EBioMedicine, 2018 Background: Resistance to chemotherapeutic treatment is a common phenomenon in cancers, especially in hepatocellular carcinoma (HCC). The Hippo signaling pathway has been demonstrated to play a role in tumor initiation, development, and progression ...
Minjiang Chen +10 more
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Circular RNA CircEPB41L2 Functions as Tumor Suppressor in Hepatocellular Carcinoma Through Sponging miR-590-5p [PDF]
Cancer Management and Research, 2021 Feng Chen,1,2 Lei He,2,3 Liman Qiu,2,3 Yang Zhou,2,3 Zhenli Li,2,3 Geng Chen,2,3 Fuli Xin,2,3 Xiuqing Dong,2,3 Haipo Xu,2,3 Gaoxiong Wang,4 Jingfeng Liu,2,3 Zhixiong Cai2,3 1College of Life Science, Fujian Agriculture and Forestry University, Fuzhou ...
Chen F +11 more
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MiR-590-5P Inhibits Growth of HepG2 Cells via Decrease of S100A10 Expression and Inhibition of the Wnt Pathway [PDF]
International Journal of Molecular Sciences, 2013 Hepatocellular carcinoma is one of the most common and lethal cancers worldwide, especially in developing countries. In the present study, we found that the expression of a microRNA, miR-590-5P, was down-regulated and S100A10 was up-regulated in six ...
Xiangxiang Shan +2 more
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Cell Journal, 2016 Objective: SMAD proteins are the core players of the transforming growth factor-beta (TGFβ) signaling pathway, a pathway which is involved in cell proliferation, differentiation and migration.
Meisam Jafarzadeh, Bahram M. Soltani
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