Results 41 to 50 of about 276,038 (194)

Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto

open access: yesJurnal Kesehatan Andalas, 2021
Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih   +2 more
doaj   +1 more source

Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients

open access: yesFrontiers in Neurology, 2022
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high disability and mortality. MicroRNAs (miRNAs) are reported to play a modulating role in aSAH.
Lina Zheng   +3 more
doaj   +1 more source

miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5

open access: yesMolecular Medicine Reports, 2018
Recently, microRNA (miR)‑590‑5p has been shown to inhibit tumorigenesis in colorectal and breast cancer; however, its function in osteosarcoma (OS) requires further investigation. In the present study miR‑590‑5p expression was poorly expressed in OS samples and cell lines when compared with that observed in normal cells.
Wei, Cai   +4 more
openaire   +3 more sources

Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility

open access: yesNon-Coding RNA, 2023
Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag   +10 more
doaj   +1 more source

MicroRNA-590-5p antagonizes the inhibitory effect of high glucose on osteoblast differentiation by suppressing Smad7 in MC3T3-E1 cells

open access: yesJournal of International Medical Research, 2019
Objective MicroRNA-590-5p (miR-590-5p) has been reported to stimulate osteoblast differentiation; however, its effect in diabetic osteoporosis remains unknown.
Yinan Chen   +6 more
doaj   +1 more source

The Impact of lncRNAs and miRNAs in Regulation of Function of Cancer Stem Cells and Progression of Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected
Soudeh Ghafouri-Fard   +5 more
doaj   +1 more source

SNHG1-miR-186-5p-YY1 feedback loop alleviates hepatic ischemia/reperfusion injury

open access: yes, 2022
As a common cause of liver injury, hepatic ischemia/reperfusion injury (HIRI) happens in various clinical conditions including trauma, hepatectomy and liver transplantation.
Qiang Sun (225630)   +5 more
core   +1 more source

The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

open access: yesStem Cell Reports, 2018
Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu   +10 more
doaj   +1 more source

The miR-590 C57T SNP reduces levels of miR-590-5p and miR-590-3p, without affecting the levels of pri-miR-590 and pre-miR-590.

open access: yes, 2016
(A) Quantification of pri-miR-590 by qRT-PCR normalized by GAPDH. Mean ± SD (n = 3). HEK293T cells were transfected with the pri-miR-590-WT or pri-miR-590-SNP plasmids. The empty plasmid was used as negative control.
Suresh K. Kandasamy (2794198)   +15 more
core   +1 more source

Identification of miR-194-5p as a potential biomarker for postmenopausal osteoporosis [PDF]

open access: yesPeerJ, 2015
The incidence of osteoporosis is high in postmenopausal women due to altered estrogen levels and continuous calcium loss that occurs with aging. Recent studies have shown that microRNAs (miRNAs) are involved in the development of osteoporosis.
Jia Meng   +8 more
doaj   +2 more sources

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