The Effect of miR-34a-5p and miR-145-5p Ectopic Expression on Cell Proliferation and Target Gene Expression in the MDA-MB-231 Cell Line [PDF]
, 2021 Aim:It was aimed to investigate the effect of miR-34a-5p and miR-145-5p on breast cancer cell line MDA-MB-231 and to determine the expression of target genes of these microRNAs (miRNAs).Materials and Methods:Firstly, literature search and in silico ...
Emre ÖZGÜR +5 more
core +1 more source
Erratum: [Corrigendum] miR‑590‑5p may regulate colorectal cancer cell viability and migration by targeting PDCD4. [PDF]
Exp Ther MedGuo T, Wang J, Cheng G, Huang H.
europepmc +2 more sources
Evaluation of BMP2/miRNA co-expression systems for potent therapeutic efficacy in bone-tissue regeneration [PDF]
European Cells & Materials, 2021 Reconstruction of bone defects and compensation of deficient repair mechanisms represent important goals within the field of regenerative medicine and require novel safe strategies for translation into the clinic.
TK Brenner +9 more
doaj +1 more source
Oncol Lett, 2021 Lung adenocarcinoma (LUAD) is the leading cause of cancer-related mortality worldwide. Long non-coding RNA (lncRNA) NUT family member 2A antisense RNA 1 (NUTM2A-AS1) is dysregulated in LUAD; however, its role in this disease remains unclear. The present study aimed to identify the underlying molecular mechanism of the effect of lncRNA NUTM2A-AS1 in ...
Wang J, Zha J, Wang X.
europepmc +4 more sources
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Journal of Immunology Research, 2022 Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou +7 more
doaj +1 more source
Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis
Frontiers in Cell and Developmental Biology, 2021 Long intergenic non-coding RNA 00657 (LINC00657) or “non-coding RNA activated by DNA damage” (NORAD) is an extremely conserved and copious long non-coding RNA (lncRNA). This transcript has pivotal role in the preservation of genome integrity.
Soudeh Ghafouri-Fard +5 more
doaj +1 more source
The Frog Skin-Derived Antimicrobial Peptide Suppresses Atherosclerosis by Modulating the KLF12/p300 Axis Through miR-590-5p. [PDF]
Int J Mol SciInflammation is a hallmark of atherosclerosis (AS), a complex chronic vascular disease. This study investigates the anti-atherosclerotic effects of the frog skin antimicrobial peptide(AMP) C-1b(3-13) in vitro and in vivo, focusing on the anti-inflammatory mechanism mediated by the miR-590-5p/KLF12/p300 axis in ox-LDL-induced PMA-THP-1 foam cells ...
Fan F, Li MM, Qiu ZP, Li ZJ, Shang DJ.
europepmc +3 more sources
Scientific Reports, 2022 Early diagnosis of breast cancer (BC), as the most common cancer among women, increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control various cell behaviors, and their dysregulation is widely involved in pathophysiological ...
Zahra Sharifi +2 more
doaj +1 more source
Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. [PDF]
PLoS ONE, 2013 AIMS: MicroRNAs (miRNAs) play important roles in the pathogenesis of cardiovascular diseases. Circulating miRNAs were recently identified as biomarkers for various physiological and pathological conditions.
Jingyi Ren +8 more
doaj +1 more source
Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto
Jurnal Kesehatan Andalas, 2021 Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih +2 more
doaj +1 more source