Downregulation of Circ-PITHD1 Suppressed Colorectal Cancer via Glycolysis Inhibition through miR-590-5p/HK2 Axis. [PDF]
Colorectal cancer (CRC) is a frequent malignancy around the globe. Circular RNAs (circRNAs) are implicated in CRC development. Nevertheless, the regulatory mechanisms and biological functions regarding circRNAs in CRC progression are largely unclear.
Yang S, Zhao K, Yang X, Xing C.
europepmc +3 more sources
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis. [PDF]
AbstractAccumulating evidences indicate that 3ʹUTR of the coding gene can act as crucial regulators in gastric cancer (GC). However, the detailed mechanisms and responsive targets are not well established. Here, we found thatacvr1bgene 3ʹUTR (acv3UTR) was elevated in GC tissue, the expression of which was significantly correlated with advanced pTNM ...
Liu K +9 more
europepmc +4 more sources
Chemokine ligand 20 (CCL20) expression increases with NAFLD stage and hepatic stellate cell activation and is regulated by miR-590-5p. [PDF]
Hanson A +7 more
europepmc +3 more sources
MiR-590-5P Inhibits Growth of HepG2 Cells via Decrease of S100A10 Expression and Inhibition of the Wnt Pathway [PDF]
Xiangxiang Shan +8 more
exaly +2 more sources
Downregulation of SOX2 may be targeted by miR-590-5p and inhibits epithelial-to-mesenchymal transition in non-small-cell lung cancer. [PDF]
Chang Z.
europepmc +3 more sources
Erratum: [Corrigendum] miR‑590‑5p may regulate colorectal cancer cell viability and migration by targeting PDCD4. [PDF]
Guo T, Wang J, Cheng G, Huang H.
europepmc +2 more sources
MicroRNAs (miRNAs/miRs) act as markers for various cancers, including bladder cancer (BC). Plasma miRNAs are potential biomarkers for the noninvasive diagnosis and long‑term surveillance of BC. The aim of the present study was to identify diagnostically reliable miRNAs in the plasma and examine their potential monitoring capacity.
Angelika T�lle +2 more
openalex +5 more sources
miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis. [PDF]
Several studies showed that assessing levels of specific circulating microRNAs (miRNAs) is a non-invasive, rapid, and accurate method for diagnosing diseases or detecting alterations in physiological conditions.
Aloi, Francesco +14 more
core +10 more sources
Evaluation of BMP2/miRNA co-expression systems for potent therapeutic efficacy in bone-tissue regeneration [PDF]
Reconstruction of bone defects and compensation of deficient repair mechanisms represent important goals within the field of regenerative medicine and require novel safe strategies for translation into the clinic.
TK Brenner +9 more
doaj +1 more source
miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5
Recently, microRNA (miR)‑590‑5p has been shown to inhibit tumorigenesis in colorectal and breast cancer; however, its function in osteosarcoma (OS) requires further investigation. In the present study miR‑590‑5p expression was poorly expressed in OS samples and cell lines when compared with that observed in normal cells.
Wei Cai +4 more
openalex +5 more sources

