Results 61 to 70 of about 276,038 (194)
, 2023 Imatinib (IM) resistance is considered to be a significant challenge in the management of chronic myeloid leukemia (CML). Previous studies have reported that hsa-miR-145-5p and hsa-miR-203a-5p can overcome IM resistance and hsa-miR-203a-5p can alter ...
Priyanka Singh (256412) +7 more
core +1 more source
Oncology Reports, 2015 MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are associated with a variety of human cancers. Currently, little data are available regarding miRNA expression in vulvar squamous cell carcinoma (VSCC); the mechanism of action of miRNAs in VSCC still requires investigation.
Xiuhua, Yang, Xin, Wu
openaire +3 more sources
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen +6 more
wiley +1 more source
Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
wiley +1 more source
miR-34a-5p affects the EZH2 protein pathway.
, 2023 (A) Binding sites of EZH2 and miR-34a-5p were predicted through bioinformatics analysis. (BⅠ-Ⅱ) Double luciferase reporter experiment confirmed this prediction.
Chengcheng Liao (12402943) +16 more
core +1 more source
Viruses, 2020 Exosomes seem to play an important role in hepatits C virus (HCV) and hepatitis E virus (HEV) infection by shielding their cargo from the host immune responses, with microRNAs being key exosomal components.
Karen McGowan +2 more
doaj +1 more source
The Role of Lightning in Atmospheric Chemistry
Journal of Geophysical Research: Atmospheres, Volume 131, Issue 16, 28 August 2026.Abstract Lightning has important effects on atmospheric constituents in primarily the middle and upper troposphere. We summarize the effects of lightning on atmospheric chemistry that have been published since the last major review in 2007. The estimates of NOx production by lightning (LNOx) are based on five methods: theoretical/laboratory estimates ...
Kenneth E. Pickering +2 more
wiley +1 more source
, 2016 (A) Multiple sequence alignment of pre-miR-590 from mammals. (B) miR-590 biogenesis pathway.
Suresh K. Kandasamy (2794198) +15 more
core +1 more source
TGIF2 expression in miR-210-5p-overexpressing cells.
, 2021 (A) Predicted miR-210-5p binding sites in the TGIF2-3`UTR. (B) HOS cells were transfected with the luciferase reporter vector of TGIF2-3`UTR (upper image) and various amounts of miR-210-5p mimic, and dual-luciferase activity was measured 30 h later. (C-D)
Lixia Huang (429197) +9 more
core +1 more source
Advanced Science, Volume 13, Issue 41, 22 July 2026.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source