Autoimmunity, 2021 Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang +5 more
doaj +1 more source
lncRNA-ATB functions as a competing endogenous RNA to promote YAP1 by sponging miR-590-5p in malignant melanoma. [PDF]
Int J Oncol, 2018 Mou K +6 more
europepmc +3 more sources
Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma [PDF]
, 2015 BACKGROUND Posttraumatic nosocomial pneumonia is a common complication resulting in significant morbidity. Trauma-induced immunocompromise is associated with an enhanced susceptibility to pneumonia.
Bartel +19 more
core +4 more sources
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Journal of Immunology Research, 2022 Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou +7 more
doaj +1 more source
Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis
Frontiers in Cell and Developmental Biology, 2021 Long intergenic non-coding RNA 00657 (LINC00657) or “non-coding RNA activated by DNA damage” (NORAD) is an extremely conserved and copious long non-coding RNA (lncRNA). This transcript has pivotal role in the preservation of genome integrity.
Soudeh Ghafouri-Fard +5 more
doaj +1 more source
FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p. [PDF]
Oncogene, 2019 Zhang J +17 more
europepmc +3 more sources
Scientific Reports, 2022 Early diagnosis of breast cancer (BC), as the most common cancer among women, increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control various cell behaviors, and their dysregulation is widely involved in pathophysiological ...
Zahra Sharifi +2 more
doaj +1 more source
SSRN Electronic Journal, 2019 Background: Resistance against radio therapy is growing concern in treating patients of pancreatic cancer (PC). Improving our depth with regards to mechanisms involved in radio resistance could help in developing strategies for increasing patient's response to this therapy.
Fazhao Li +4 more
openalex +2 more sources
Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. [PDF]
PLoS ONE, 2013 AIMS: MicroRNAs (miRNAs) play important roles in the pathogenesis of cardiovascular diseases. Circulating miRNAs were recently identified as biomarkers for various physiological and pathological conditions.
Jingyi Ren +8 more
doaj +1 more source
MicroRNA expression profiles in human CD3+ T cells following stimulation with anti‑human CD3 antibodies [PDF]
, 2017 Background: Anti-CD3 therapy can induce immunosuppression by several non mutually exclusive mechanisms that have been proposed to explain the therapeutic effect the administration anti-CD3 mAb, but its immunoregulatory mechanism is still not completely ...
Almo, Manuela Maragno do +6 more
core +2 more sources