Results 51 to 60 of about 276,038 (194)

MiR-942-5p regulates the expression of CST1.

, 2023
(A) Conserved binding sites of four miRNAs to CST1 sequences. (B) Expression of miR-942-5p in 7 cell lines. (C) Expression of miR-942-5p after transfection of mimics. (D) Expression of miR-942-5p after transfection of inhibitor.
Yi Zhang (9093), Xiaoqing Yin (2657140), Liqing Cai (13241958), Lili Yu (149552), Liangming Zhang (105007), Yi Huang (112882), Sunxing Yu (11978399), Mingshu Tu (13241955), Xiaojie Pan (3821062), Songgao Zhang (14684569)   +9 more
core   +1 more source

Potential Predictive Value of miR-125b-5p, miR-155-5p and Their Target Genes in the Course of COVID-19

, 2022
Xuewen Li,1 Yiting Wang,1 Qi Zhou,2 Junqi Pan,3 Jiancheng Xu1 1Department of Laboratory Medicine, First Hospital of Jilin University, Changchun, People’s Republic of China; 2Department of Pediatrics, First Hospital of Jilin University, Changchun, People ...
Li X, Pan J, Zhou Q, Wang Y, Xu J
core  

MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements

Cellular Physiology and Biochemistry, 2018
Background/Aims: MicroRNA (miRNA)-induced suppression of dendritic cells (DCs) has been implicated in many diseases. Therefore, accurate monitoring of miRNA endocytosis by DCs is important for understanding the role of miRNAs in many diseases.
Qiang Tong, Ying Zhu, Dandan Zhang, Qing Cai, Wenchun Qu, Christopher D. O. Cooper, Jiaqi Wang, Patrick C. McHugh   +7 more
doaj   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

Frontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno, Triin Kikas, Kristiina Lillepea, Maris Laan   +3 more
doaj   +1 more source

Construction of a Nine-MicroRNA-Based Signature to Predict the Overall Survival of Esophageal Cancer Patients

Frontiers in Genetics, 2021
BackgroundEsophageal cancer (EC) is a common malignant tumor. MicroRNAs (miRNAs) play a key role in the occurrence and metastasis and are closely related to the prognosis of EC.
Xiaobin Zhang, Xiaobin Zhang, Yi He, Haiyong Gu, Zhichao Liu, Bin Li, Yang Yang, Jie Hao, Rong Hua   +8 more
doaj   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The miR-590 C57T SNP reduces target suppression by miR-590.

, 2016
Silencing of Renilla luciferase reporters bearing 3′ UTR target sites for miR-590-5p. Reporters containing four tandemmiR-590-5p perfect match sites with t1A (A), four tandemmiR-590-5p near perfect match sites with mismatches at positions 9–11 and t1A (B)
Suresh K. Kandasamy (2794198), Steven Steinberg (582816), Scot J. Matkovich (421129), Neal Epstein (2794180), Dotti Tripodi (2794204), Garry Cutting (2794201), Xiaoping Lin (215407), Blaid Mbiyangandu (2794195), Celia P. Corona-Villalobos (2794189), Ryuya Fukunaga (2794186), M. Roselle Abraham (242563), Junaid Afzal (2794192), Susan E. Liao (2794177), Yufan Guan (2794171), Zhaoxia Huo (2794183), Theodore P. Abraham (2794174)   +15 more
core   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source