Results 31 to 40 of about 6,232 (244)

The importance of miRNA-630 in human diseases with an especial focus on cancers

Cancer Cell International, 2022
miR-630 is encoded by MIR630 gene (NC_000015.10) on 15q24.1. This miRNA is mostly associated with cytokine signaling in immune system. Several neoplastic as well as non-neoplastic conditions have been linked with dysregulation of miR-630.
Sepideh Kadkhoda, Soudeh Ghafouri-Fard
doaj   +1 more source

Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease [PDF]

, 2013
Background: Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications.
A Abdollahi, A Dixon-McIver, A Osman, A Schedel, A Smolenski, A Tomer, AA Kondkar, AD Blann, AI Badeaux, AJ Saldanha, AM Healy, BM Steele, Claudia Coronnello, D Betel, D Betel, DA Hosack, DP Bartel, DV Gnatenko, EM Novelli, ER Popescu, G Bazzoni, Gregory J. Kato, Guoying Yu, H Bruchova, H Seitz, HA Brittain, I Hers, I Toma, J Villagra, Jen-Tsan Ashley Chi, JF Noronha, JS Mohan, K Joop, K Kaushansky, K Konishi, Kimberly Woodhouse, LL Horstman, LR Queen, M Kannan, M Kertesz, Maria G. Kapetanaki, Mark T. Gladwin, MC Ammons, ML Freedman, ML Jison, MP Hunter, N Chavda, N Raghavachari, Naftali Kaminski, Nalini Raghavachari, P Landry, Panayiotis V. Benos, PV Browne, R Antonucci, R Garzon, R Ross, R Visone, RC Friedman, RJ Berckmans, RL Nachman, RT Schermuly, S Amisten, S Kim, S Masaki, S Mendjan, S Nagalla, Shilpa Jain, SP Lee, Suchitra Barge, T Wun, V Ambros, W Huang da   +71 more
core   +16 more sources

Circular RNA CircMTO1 suppressed proliferation and metastasis of osteosarcoma through miR-630/KLF6 axis.

European review for medical and pharmacological sciences, 2021
Circular RNAs (circRNAs) could regulate gene expression which may induce tumor occurrence and progression. In the current study, we first investigated the expression of circMTO1 in osteosarcoma, and the underlying mechanism was further elucidated.Circular RNA microarrays were used to identify the differential expression of circRNAs in osteosarcoma ...
Liu, D.-Y., Li, Z., Zhang, K., Jiao, N., Lu, D.-G., Zhou, D.-W., Meng, Y.-B., Sun, L.   +7 more
openaire   +2 more sources

Identification and validation of circulating miRNAs as potential new biomarkers for severe liver disease in patients with leptospirosis.

PLoS ONE, 2021
BackgroundLeptospirosis, a global zoonotic infectious disease, has various clinical manifestations ranging from mild self-limiting illness to life-threatening with multi-organ damage, including liver involvement.
Natthaya Chuaypen, Umaporn Limothai, Pattapon Kunadirek, Pornchai Kaewsapsak, Patipark Kueanjinda, Nattachai Srisawat, Pisit Tangkijvanich   +6 more
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The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]

, 2014
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu, Wenbin eDeng, Wenbin eDeng, Wenrong eGong, Xin eQin   +4 more
core   +2 more sources

Impact of microRNAs in Resistance to Chemotherapy and Novel Targeted Agents in Non-Small Cell Lung Cancer [PDF]

, 2014
Despite recent advances in understanding the cancer signaling pathways and in developing new therapeutic strategies, non-small cell lung cancer (NSCLC) shows grim prognosis and high incidence of recurrence.
BAZAN, Viviana, CARUSO, Stefano, CICERO, Giuseppe, FANALE, Daniele, Giovannetti, E., Hong, D, Meerbeeck, J, Pauwels, P, Piha Paul, S, Rolfo, C, RUSSO, Antonio, Tsimberidou, A   +11 more
core   +8 more sources

Tissue miR-200c-3p and circulating miR-1290 as potential prognostic biomarkers for colorectal cancer

Scientific Reports, 2022
Epithelial–mesenchymal transition (EMT)-related cancers generally elicit low immune responses. EMT is regulated by several microRNAs (miRNAs) in cancers.
Enoch Kang, Sung Cheol Jung, Soo Kyung Nam, Yujun Park, Soo Hyun Seo, Kyoung Un Park, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Hye Seung Lee   +9 more
doaj   +1 more source

Monocyte subpopulations display disease-specific miRNA signatures depending on the subform of Spondyloarthropathy

Frontiers in Immunology, 2023
Spondyloarthropathies (SpA) are a family of rheumatic disorders that could be divided into axial (axSpA) and peripheral (perSpA) sub-forms depending on the disease clinical presentation.
Małgorzata Stec, Marcin Czepiel, Marzena Lenart, Agata Piestrzyńska-Kajtoch, Jacek Plewka, Agnieszka Bieniek, Kazimierz Węglarczyk, Rafał Szatanek, Magdalena Rutkowska-Zapała, Zofia Guła, Anna Kluczewska, Jarosław Baran, Mariusz Korkosz, Maciej Siedlar   +13 more
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Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells [PDF]

, 2018
Indexación: Scopus.Departamento de Oncología Básico-Clínica, Facultad de Medicina, Universidad de Chile, Santiago, Chile 2Comisión Chilena de Energía Nuclear, Santiago, Chile 3Center for Research and Applications in Plasma Physics and Pulsed Power, P4 ...
Andaur, R., Armisen, R., Marcelain, K., Moreno, J., Soto, L., Tapia, J.C.   +5 more
core   +1 more source

Relationship Between Coronary Atheroma, Epicardial Adipose Tissue Inflammation, and Adipocyte Differentiation Across the Human Myocardial Bridge

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin, Ingela Schnittger, Anna Nagy, Elizabeth Zanley, Yue Xu, Yanqiu Song, Koen Nieman, Jennifer A. Tremmel, Damini Dey, Jack Boyd, Harold Sacks   +10 more
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