Results 11 to 20 of about 461,417 (302)

Deciphering miRNAs’ Action through miRNA Editing [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation. The outcome of a myriad of physiological processes and pathologies, including cancer, cardiovascular and metabolic diseases, relies ...
Correia De Sousa, Marta   +4 more
openaire   +3 more sources

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions [PDF]

open access: yesBioMed Research International, 2014
MicroRNAs (miRNAs) are small, noncoding regulatory molecules. They are involved in many essential biological processes and act by suppressing gene expression. The present work reports an integrative analysis of miRNA-mRNA and miRNA-miRNA interactions and their regulatory patterns using high-throughput miRNA and mRNA datasets. Aberrantly expressed miRNA
Guo, Li   +4 more
openaire   +2 more sources

Regulation of miRNA content. Part 1. Editing miRNA. Тailing miRNA

open access: yesCHILD`S HEALTH, 2022
This scientific review presents the processes of regulation of miRNA content. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases.
A.E. Abaturov, V.L. Babуch
openaire   +4 more sources

MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2016
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng   +7 more
openaire   +2 more sources

The singular world of singular cardinals [PDF]

open access: yes, 2014
The article uses two examples to explore the statement that, contrary to the common wisdom, the properties of singular cardinals are actually more intuitive than those of the regular ...
Dzamonja, Mirna
core   +2 more sources

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer [PDF]

open access: yesFrontiers in Oncology, 2015
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures. Accumulating evidence indicates that miRNA expression patterns represent the in vivo status in physiology and
Xin eQin   +4 more
openaire   +5 more sources

Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration. [PDF]

open access: yes, 2012
BACKGROUND: Adaptation to chronic ethanol (EtOH) treatment of rats results in a changed functional state of the liver and greatly inhibits its regenerative ability, which may contribute to the progression of alcoholic liver disease.
Dippold, Rachael P   +4 more
core   +2 more sources

Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma

open access: yesClinical Neurology and Neurosurgery, 2017
Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular ...
Katar, Salim   +8 more
openaire   +3 more sources

The impact of plasmid on regeneration and expression efficiencies of gfp gene in tobacco (Nicotiana tabacum L.)

open access: yesActa Agriculturae Slovenica, 2014
Tobacco leaf explants were transformed by bacteria Agrobacterium tumefaciens (A. t.) and plasmid pBIN mgfp5-ER, which has a single copy of the green fluorescent gfp gene and A. t.-pART27 2mgfp5-ER, which has two copies of the gfp gene. Both plasmids have
Niko PAVLIN, Zlata LUTHAR
doaj   +1 more source

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

open access: yesCells, 2020
In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC).
Lisa Linck-Paulus   +3 more
doaj   +1 more source

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