Results 21 to 30 of about 461,417 (302)
Administration of Insurance Rate Regulatory Laws [PDF]
microRNAs (miRNAs) are key posttranscriptional regulators of gene expression. In the present study, regulation of tumor-suppressor gene D-glucuronyl C5-epimerase (GLCE) by miRNA-218 was investigated. Significant downregulation of miRNA-218 expression was
Ernberg, Ingemar +5 more
core +3 more sources
Core clock genes, such asBmal1, are expressed in astrocytes, but their contribution to the timekeeping system is unknown. Barca-Mayo et al. report that deletion of Bmal1in Glast+ astrocytes alters the neuronal clock through GABA signalling, leading to ...
Olga Barca-Mayo +5 more
doaj +1 more source
Representation of an absent space: construction of the United States and New York in 1950s and 1960s Czech travel writing [PDF]
Early postwar Czech travel writing was mainly concerned with representations of countries from the newly emerging Soviet Bloc and former European colonies in the developing world.
Solic, Mirna
core +1 more source
DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these
Nadin Hoffmann +4 more
doaj +1 more source
NGR4 and ERBB4 as Promising Diagnostic and Therapeutic Targets for Metabolic Disorders
Obese individuals are at high risk for developing type 2 diabetes mellitus, cardiovascular diseases, and nonalcoholic fatty liver disease. The aim of this review was to analyze the scientific literature and databases to reveal the fundamental role of ...
Maria Vulf +10 more
doaj +1 more source
Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosis [PDF]
MicroRNAs (miRNA) are a novel class of small noncoding single-stranded RNA molecules that regulate gene expression. There is increasing evidence of their importance in polycystic ovary syndrome (PCOS). The objective was to determine if miRNA-93 and miRNA-
Atkin, S. L. +3 more
core +1 more source
Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several treatment options are available including surgery, along with adjuvant chemo and radiotherapy, the disease has a poor prognosis and patients generally die within 14 months of diagnosis. GB is chemo and radio resistant.
Swalih P. Ahmed +2 more
openaire +3 more sources
The importance of training in contemporary organizations
This paper describes the concepts of training and career development for employees, level of knowledge of workers, the profit that some companies had from continuous training, and the way in which an organizational psychologist, with the support of ...
Ana Slavković, Vukan Slavković
doaj +1 more source
MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme
Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire resistance towards anoikis during tumorigenesis to become ...
Sharan Malagobadan +2 more
doaj +1 more source
Exposure to metals increases risk for pregnancy complications. Extracellular vesicle (EV) miRNA contribute to maternal-foetal communication and are dysregulated in pregnancy complications.
Caitlin G. Howe +8 more
doaj +1 more source

