Results 21 to 30 of about 487,200 (353)
Glial Bmal1 role in mammalian retina daily changes
Scientific Reports, 2022 Visual information processing in the retina requires the rhythmic expression of clock genes. The intrinsic retinal circadian clock is independent of the master clock located in the hypothalamic suprachiasmatic nucleus and emerges from retinal cells ...
Serena Riccitelli +8 more
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Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
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microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]
, 2014 BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P +5 more
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Deciphering miRNAs’ Action through miRNA Editing [PDF]
International Journal of Molecular Sciences, 2019 MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation. The outcome of a myriad of physiological processes and pathologies, including cancer, cardiovascular and metabolic diseases, relies ...
Correia De Sousa, Marta +4 more
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Animal Health Production and Hygiene, 2021 The number of uncoded (non-coding; nc) RNAs with unknown functions is increasing. Since their first detections especially miRNA of ncRNAs have become very important. In fact, their importance has been well understood and their relations with diseases are more evident. It is clear that they can be used in the diagnosis of most diseases in the future.
SUVARIKLI ALAN, Beyza +2 more
openaire +4 more sources
The American Journal of Pathology, 2009 Cancer is the result of a complex multistep process that involves the accumulation of sequential alterations of several genes, including those encoding microRNAs (miRNAs). miRNAs are a class of 17- to 27-nucleotide single-stranded RNA molecules that regulate gene expression posttranscriptionally.
Rosa Visone, Carlo M. Croce
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Biology of Polyomavirus miRNA [PDF]
Frontiers in Microbiology, 2021 Polyomaviruses are a family of non-enveloped DNA viruses with wide host ranges. Human polyomaviruses typically cause asymptomatic infection and establish persistence but can be reactivated under certain conditions and cause severe diseases. Most well studied polyomaviruses encode a viral miRNA that regulates viral replication and pathogenesis by ...
Michael J. Imperiale, Wei Zou
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miR-34 – A microRNA Replacement Therapy Is Headed to the Clinic
Frontiers in Genetics, 2012 MicroRNA-34 is a master regulator of tumor suppression. It is downregulated in numerous cancers and inhibits malignant growth by repressing genes involved in various oncogenic signaling pathways.
Andreas G Bader
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Epigenetics, 2022 Circulating miRNA may contribute to the development of adverse birth outcomes. However, few studies have investigated extracellular vesicle (EV) miRNA, which play important roles in intercellular communication, or compared miRNA at multiple time points ...
Caitlin G Howe +12 more
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Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosis [PDF]
, 2015 MicroRNAs (miRNA) are a novel class of small noncoding single-stranded RNA molecules that regulate gene expression. There is increasing evidence of their importance in polycystic ovary syndrome (PCOS). The objective was to determine if miRNA-93 and miRNA-
Atkin, S. L. +3 more
core +1 more source