Results 61 to 70 of about 332,353 (158)

DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites [PDF]

, 2016
The DISC1 protein is implicated in major mental illnesses including schizophrenia, depression, bipolar disorder, and autism. Aberrant mitochondrial dynamics are also associated with major mental illness.
Atkin, TA, Birsa, N, Hirst, WD, Ivankovic, D, Kittler, JT, Korth, C, Modi, S, Norkett, R, Pathania, M, Trossbach, SV   +9 more
core  

Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling. [PDF]

, 2020
Organisms respond to tissue damage through the upregulation of protective responses which restore tissue structure and metabolic function. Mitochondria are key sources of intracellular oxidative metabolic signals that maintain cellular homeostasis.
Chisholm, Andrew D, Fu, Hongying, Meng, Xinan, Xu, Jingxiu, Xu, Suhong, Yu, Xinghai, Zhao, Jianzhi, Zhou, Hengda, Zhou, Jinghua, Zhou, Yu   +9 more
core  

Extra-matrix Mg\u3csup\u3e2+\u3c/sup\u3e Limits Ca\u3csup\u3e2+\u3c/sup\u3e Uptake and Modulates Ca\u3csup\u3e2+\u3c/sup\u3e Uptake-independent Respiration and Redox State in Cardiac Isolated Mitochondria [PDF]

, 2013
Cardiac mitochondrial matrix (m) free Ca2+ ([Ca2+]m) increases primarily by Ca2+ uptake through the Ca2+ uniporter (CU). Ca2+ uptake via the CU is attenuated by extra-matrix (e) Mg2+ ([Mg2+]e).
Blomeyer, Christoph A., Boelens, Age D., Camara, Amadou K.S., Dash, Ranjan K., Pradhan, Ranjan K., Stowe, David F.   +5 more
core   +1 more source

Removal of the Mitochondrial Fission Factor Mff Exacerbates Neuronal Loss and Neurological Phenotypes in a Huntington’s Disease Mouse Model [PDF]

, 2018
Objective: Excessive mitochondrial fission has been associated with several neurodegenerative diseases, including Huntington’s disease (HD). Consequently, mitochondrial dynamics has been suggested to be a promising therapeutic target for Huntington’s ...
Cha, Moon Yong, Chan, David, Chen, Hsiuchen   +2 more
core  

Mitochondrial dynamics in heart disease

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013
Mitochondrial fission and fusion have been observed, and their importance revealed, in almost every tissue and cell type except adult cardiac myocytes. As each human heart is uniquely dependent upon mitochondria to generate massive amounts of ATP that fuel its approximately 38 million contractions per year, it seems odd that cardiac myocytes are the ...
openaire   +2 more sources

Mitochondrial Dynamics for Pollen Development

Plant Physiology, 2019
Mitochondria are active organelles that move rapidly, change shape, and undergo repeated fusion and fission ([Frederick and Shaw, 2007][1]; [Tilokani et al., 2018][2]). Since mitochondria have many important roles, including respiratory energy production through the tricarboxylic acid cycle ...
openaire   +3 more sources

Mitochondrial Dynamics in Aging Heart. [PDF]

Biomedicines
Patyal P, Azhar G, Verma A, Sharma S, Shrivastava J, Abdi SAH, Zhang X, Wei JY.   +7 more
europepmc   +1 more source

Features of Mitochondrial Dynamics in Different Brain Parts of Patients with Alzheimer's Disease. [PDF]

Int J Mol Sci
Sukhorukov VS, Baranich TI, Velts OV, Voronkov DN, Shcherbak EV, Lazarev DS, Kharlamov DA, Raksha AP.   +7 more
europepmc   +1 more source

Mitochondrial dynamics in cisplatin resistance: molecular mechanisms and therapeutic targeting. [PDF]

Front Oncol
Huang W, Sun W, Yang Z, Li Y, Wang Z.
europepmc   +1 more source

Mitochondrial dynamics and function in neural differentiation: a systematic review. [PDF]

Eur J Med Res
Armat A, Pooladi A, Seyedoshohadaei SA, Moradveisi B, Khanyabzadeh M, Badri S, Rahimi Darehbagh R.   +6 more
europepmc   +1 more source