Results 61 to 70 of about 1,859,766 (381)

Advances in exercise to alleviate sarcopenia in older adults by improving mitochondrial dysfunction

open access: yesFrontiers in Physiology, 2023
Sarcopenia is a chronic degenerative disease affecting primarily older adults. A growing aging population is gradually increasing the number of patients suffering from sarcopenia, placing increasing financial pressure on patients’ families and society in
Yang Zhu   +5 more
doaj   +1 more source

Research Progress on the Relationship between Mitochondrial Dysfunction and Post-stroke Depression [PDF]

open access: yesZhongguo quanke yixue, 2022
Post-stroke depression (PSD) is one of the most common emotional disorders that occurs after cerebrovascular diseases, with core symptoms mainly including low mood, loss of interest, and behavioral inhibition.
Zhimin DING, Kaiqi SU, Jing GAO, Tingyu CHEN, Yixuan FENG, Xiaodong FENG
doaj   +1 more source

Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. [PDF]

open access: yes, 2016
Mitochondria abnormalities in skeletal muscle may contribute to frailty and sarcopenia, commonly present in patients with chronic kidney disease (CKD).
Billings, Frederic T   +9 more
core   +1 more source

Geniposide Protects Primary Cortical Neurons against Oligomeric Aβ1-42-Induced Neurotoxicity through a Mitochondrial Pathway. [PDF]

open access: yesPLoS ONE, 2016
Mitochondrial dysfunction plays a key role in the progression of Alzheimer's disease (AD). The accumulation of amyloid-beta peptide (Aβ) in the brains of AD patients is thought to be closely related to neuronal mitochondrial dysfunction and oxidative ...
Chunhui Zhao   +7 more
doaj   +1 more source

Mitochondrial dysfunction: mechanisms and advances in therapy

open access: yesSignal Transduction and Targeted Therapy
Mitochondria, with their intricate networks of functions and information processing, are pivotal in both health regulation and disease progression.
Yao Zong   +9 more
semanticscholar   +1 more source

Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always [PDF]

open access: yes, 2017
Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs deputed to non-image forming functions of the eye such as synchronization of circadian rhythms to light-dark cycle.
Carelli, Valerio   +7 more
core   +1 more source

Mitochondrial Regulation of Diabetic Kidney Disease

open access: yesFrontiers in Medicine, 2021
The role and nature of mitochondrial dysfunction in diabetic kidney disease (DKD) has been extensively studied. Yet, the molecular drivers of mitochondrial remodeling in DKD are poorly understood.
Daniel L. Galvan   +4 more
doaj   +1 more source

Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches

open access: yesGeroScience
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has introduced the medical community to the phenomenon of long COVID, a condition characterized by persistent symptoms following the resolution of the acute phase of infection.
T. Molnár   +9 more
semanticscholar   +1 more source

TREM1/3 deficiency impairs tissue repair after acute kidney injury and mitochondrial metabolic flexibility in tubular epithelial cells [PDF]

open access: yes, 2019
Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and the development of chronic kidney disease (CKD), which can be mediated by aberrant innate immune activation, mitochondrial pathology, and ...
Borrelli, Cristiana   +10 more
core   +2 more sources

Striatal neuroinflammation promotes parkinsonism in rats [PDF]

open access: yes, 2008
The specific role of neuroinflammation in the pathogenesis of Parkinson's disease remains to be fully elucidated. By infusing lipopolysaccharide (LPS) into the striatum, we investigated the effect of neuroinflammation on the dopamine nigrostriatal ...
Don Gash   +9 more
core   +6 more sources

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