Results 171 to 180 of about 41,598 (256)

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Astaxanthin mitigates cardiac toxicity induced via doxorubicin by alleviating mitochondrial fission and autophagy in rats. [PDF]

Sci Rep
He Y, Wu D, Wu Q, Huang S, Zhan Y, Deng J, Chen JY, Xie L, Zheng J.   +8 more
europepmc   +1 more source

Generating energy with mitochondrial fission [PDF]

Nature Cell Biology, 2014
openaire   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Mitochondrial fission factor drives an actionable metabolic vulnerability in multiple myeloma. [PDF]

Haematologica
Cantafio MEG, Valentino I, Torcasio R, Ganino L, Veneziano C, Murfone P, Mesuraca M, Perrotta I, Tallarigo F, Agosti V, De Marco C, Pasqua T, Giallongo C, Cappello AR, Fiorillo M, Gentile M, Tibullo D, Viglietto G, Neri A, Amodio N.   +19 more
europepmc   +1 more source

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

Plant-specific mitochondrial fission machinery connects mitochondrial dynamics and mitophagosome formation for piecemeal mitophagy. [PDF]

Proc Natl Acad Sci U S A
Ma J, Li C, Ren K, Zhang K, Feng L, Law KC, Chung KK, Bing Y, Gao C, Kang BH, Zhuang X.   +10 more
europepmc   +1 more source

Mitochondrial fission requires DRP1 but not dynamins

Nature, 2019
Tiago Branco Fonseca, Ángela Sánchez-Guerrero, Ira Milosevic, Nuno Raimundo   +3 more
openaire   +3 more sources

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

The mitochondrial E3 ligase MAPL SUMOylates Drp1 to facilitate mitochondrial fission in intervertebral disc degeneration. [PDF]

Bone Res
Lin Z, Lu X, Xu G, Song J, Wang H, Xia X, Lu F, Jiang J, Zhu W, Yu Z, Ma X, Zou F.   +11 more
europepmc   +1 more source