Blue Light Induces Retinal Ganglion Cell Damage by Stimulating Drp1-Dependent Mitochondrial Fission and Activating NF-κB/NOX4 Axis. [PDF]
Han XH +9 more
europepmc +1 more source
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway +6 more
wiley +1 more source
IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis. [PDF]
Cai H, He J.
europepmc +1 more source
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
MTFR2 regulated the proliferation, apoptosis, migration, and invasion of endometrial cancer cells through the Drp1/MFN1 signaling pathway mediated mitochondrial fission. [PDF]
Bai X, Wei M, Wang Q, Yang Y.
europepmc +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages. [PDF]
Abrol R +18 more
europepmc +1 more source
Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony
ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Karin Ljung +4 more
wiley +1 more source
This study reported the effect of Mito‐TEMPO on rooster semen quality cryopreserved in Beltsville extender. Semen diluted in extenders containing 10 or 100 µM of Mito‐TEMPO presented higher motility, average path velocity as well as membrane/acrosome integrity, mitochondrial activity, and fertility rate; and lower lipid peroxidation, apoptosis rate ...
Mahdi Mokhtari +3 more
wiley +1 more source
Sirtuin 4 Knockout Aggravates Sepsis-Induced Acute Liver Injury by Enhancing Mitochondrial Fission and Mitophagy in Hepatocytes. [PDF]
Li N, Ma D, Luo S, He A, Chang S.
europepmc +1 more source

