Results 191 to 200 of about 41,598 (256)

Mitochondrial fission and stemness in prostate cancer

Aging, 2019
Civenni, Gianluca, Carbone, Giuseppina M., Catapano, Carlo V.   +2 more
openaire   +2 more sources

Comparative Genomics Provide Insights Into Karyotype Evolution in Vespertilionid Bats (Vespertilionidae, Chiroptera)

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Studies elucidating the molecular basis and evolutionary consequences of karyotypic changes in mammals remain scarce. Here, we investigate chromosomal evolution by focusing on two contrasting lineages within the family Vespertilionidae (Chiroptera): the karyotypically variable tribe Pipistrellini and the highly conserved genus Myotis ...
Linjing Lan, Xin Zhang, Jinjin Xie, Xiaohui Lin, Xihong Hong, Wenhui Nie, Jinhuan Wang, Weiting Su, Fengtang Yang, Guimei He, Xiuguang Mao   +10 more
wiley   +1 more source

Intratracheal Instillation of Silver Nanoparticles to Rats Induces Mitochondrial Fission and Aortic Damage: Protective Effect of Sodium Selenite. [PDF]

Int J Nanomedicine
He S, Li PA, He J, Wang Z, Liang X, He Z, Jia S, Ma W.   +7 more
europepmc   +1 more source

Role of Succinate Dehydrogenase in Age‐Related Th17 Inflammation

Aging Cell, Volume 25, Issue 4, April 2026.
Age‐induced mitoSTAT3‐dependent upregulation of mitochondrial complex II; succinate dehydrogenase (SDH), in CD4+ T cells promotes an imbalance in the levels of metabolites succinate and fumarate, characterized by lower succinate and higher fumarate. Changes in the metabolites alter mitochondrial structure and function and promote HIF1α to induce the ...
Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica‐Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath   +17 more
wiley   +1 more source

GNPAT/USP30 Stabilizes DRP1 Protein to Promote Mitochondrial Fission and Functional Damage in COPD Progression. [PDF]

Kaohsiung J Med Sci
Cheng XG, Liu YC, Chen F, Li JW, Yao XZ, Chen QY.   +5 more
europepmc   +1 more source

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan, John Noone, Charlotte Brun, Laura Cussonneau, Alexandre Geffroy, Cecile Coudy‐Gandilhon, Isabelle Chery, Alina Lynn Evans, Jon Martin Arnemo, Jonas Kindberg, Guillemette Gauquelin‐Koch, Donal O'Gorman, Etienne Lefai, Fabrice Bertile   +13 more
wiley   +1 more source

Promotion of pathological cardiac remodeling by excessive mitochondrial fission in physical inactivity and myocardial infarction. [PDF]

Sci Rep
Miyao M, Oshima H, Kawai C, Furukawa S, Kotani H, Minami H, Abiru H, Nagai H, Yanagisawa H, Ono K, Tamaki K, Nishitani Y.   +11 more
europepmc   +1 more source

Dapansutrile preserves pancreatic beta‐cell function by regulating insulin vesicle membrane fusion and mitochondrial homeostasis

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3054-3069, April 2026.
Abstract Aims/Hypothesis Pancreatic beta‐cell dysfunction is pivotal in diabetes pathogenesis, with the NOD‐like receptor protein 3 (NLRP3) inflammasome playing a crucial role. Dapansutrile (DAPA), a novel NLRP3 inhibitor, demonstrates promise in diabetes management.
Ying Wu, Hongxing Fu, Min Zhu, Yuanfa Yao, Luhong Jin, Xihua Lin, Jiaqiang Zhou   +6 more
wiley   +1 more source

Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis. [PDF]

Stem Cell Res Ther
Li T, Guo C, Liu Q, Jing F, Zhao M, Xiong H, Li C, Zhang W, Chen B.   +8 more
europepmc   +1 more source

Baicalin Improves Skeletal Muscle Atrophy by Attenuating DRP-1-Mediated Mitochondrial Fission in Aged Mice. [PDF]

Muscles
Mo HMM, Lee JH.
europepmc   +1 more source