Results 271 to 280 of about 77,225 (305)

Retraction: Inhibition of mitochondrial fission as a novel therapeutic strategy to reduce mortality upon myocardial infarction. [PDF]

Clin Sci (Lond)
europepmc   +1 more source

Drp1 mitochondrial fission in astrocyte modulates behavior and neuroinflammation during morphine addiction. [PDF]

J Neuroinflammation
Gu X, Chen W, Li Z, Wang X, Su Q, Zhou F.   +5 more
europepmc   +1 more source

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Mitochondrial fission in apoptosis

Nature Reviews Molecular Cell Biology, 2005
Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.
Richard J, Youle, Mariusz, Karbowski
openaire   +2 more sources

Mitochondrial fission and fusion

Biochemical Society Transactions, 2016
Mitochondrial fission and fusion have been recognized as critical processes in the health of mitochondria and cells. Two decades of studies have generated a great deal of information about mitochondrial fission and fusion; however, still much needs to be understood for the basic molecular mechanisms of these important cellular processes.
Hakjoo, Lee, Yisang, Yoon
openaire   +2 more sources

Mitochondrial fission and fusion

Biochemistry (Moscow), 2015
Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria.
M V, Patrushev, I O, Mazunin, E N, Vinogradova, P A, Kamenski   +3 more
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Mitochondrial Fission Mediates Endothelial Inflammation

Hypertension, 2020
Endothelial inflammation and mitochondrial dysfunction have been implicated in cardiovascular diseases, yet, a unifying mechanism tying them together remains limited. Mitochondrial dysfunction is frequently associated with mitochondrial fission/fragmentation mediated by the GTPase Drp1 (dynamin-related protein 1).
Steven J, Forrester, Kyle J, Preston, Hannah A, Cooper, Michael J, Boyer, Kathleen M, Escoto, Anthony J, Poltronetti, Katherine J, Elliott, Ryohei, Kuroda, Masashi, Miyao, Hiromi, Sesaki, Tomoko, Akiyama, Yayoi, Kimura, Victor, Rizzo, Rosario, Scalia, Satoru, Eguchi   +14 more
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Mitochondrial fission fueled by fasting

Science Signaling, 2023
Fasting activates mTORC2 to stimulate mitochondrial fission and support mitochondrial respiration.
openaire   +2 more sources

Quantifying Regulated Mitochondrial Fission in Macrophages

2022
Mitochondria have co-evolved with eukaryotic cells for more than a billion years, becoming an important cog in their machinery. They are best known for being tasked with energy generation through the production of adenosine triphosphate, but they also have roles in several other cellular processes, for example, immune and inflammatory responses ...
Afroz, Syeda Farhana, Condon, Nicholas, Sweet, Matthew, Kapetanovic, Ronan   +3 more
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miR‐376b‐3p attenuates mitochondrial fission and cardiac hypertrophy by targeting mitochondrial fission factor

Clinical and Experimental Pharmacology and Physiology, 2018
SummaryMitochondrial dysfunction contributes to the pathogenesis of cardiac hypertrophy. The disequilibrium of mitochondrial dynamic, which refers to mitochondrial fusion and fission, leads to mitochondrial morphology alteration and dysfunction. Enhanced understanding of the molecular mechanisms in depth may shed light on the therapy of the disease. In
Yong Le Sun, Shao Hua Li, Le Yang, Yong Wang   +3 more
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Intersection between Mitochondrial Permeability Pores and Mitochondrial Fusion/Fission

Neurochemical Research, 2007
The goal of this review is to highlight recent developments in the field of mitochondrial membrane processes, which provide new insights into the relation between mitochondrial fission/fusion events and the mitochondrial permeability transition (MPT).
Irina G, Gazaryan, Abraham M, Brown
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