The Journal of Physiology, EarlyView.Abstract figure legend The mechanisms underpinning improved maximal oxygen uptake following sprint interval training (SIT) with post‐exercise blood flow restriction (BFR), compared to SIT alone, remain unclear. This study examined the effects of 6 week SIT with (BFR; n = 12) or without (CON; n = 8) post‐exercise BFR on V̇O2peak${{\dot{V}}_{{{{\mathrm{O}
Donald L. Peden +4 more
wiley +1 more source
Mitochondrial Dynamics in Cancer Progression and Therapy Resistance: Emerging Roles in Metabolic Reprogramming, Biomarker Discovery, and Precision Medicine. [PDF]
CellsPenugurti V, Kant R, Hsu CC.
europepmc +1 more source
MedComm – Oncology, Volume 5, Issue 3, September 2026.Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
TRMT10C promotes mitochondrial fission through transferrin receptor m1A methylation modification and aggravates the progression of atrial fibrillation. [PDF]
J Cell Commun SignalLi N, Zhang H.
europepmc +1 more source
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
Biological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy, primarily affecting skeletal muscle and leading to premature death. Although the loss of dystrophin has long been recognised as the primary cause of the disease, no definitive cure is currently available. As a consequence, therapeutic efforts
Raffaele Epis +5 more
wiley +1 more source
The role of mitochondrial dynamics in metabolic dysfunction-associated steatotic liver disease. [PDF]
Front Med (Lausanne)Yang N, Hao Y.
europepmc +1 more source
Mitochondrial membrane remodeling in stress adaptation: Lipid control of organelle quality
Protein Science, Volume 35, Issue 8, August 2026.Abstract Mitochondria respond to proteotoxic stress through the mitochondrial unfolded protein response, traditionally viewed as a transcriptional program that restores proteostasis by inducing chaperones and proteases. Emerging evidence indicates that mitochondrial membrane remodeling constitutes an additional adaptive component of this response ...
Lena J. Reichert +2 more
wiley +1 more source
Mechanisms by Which Exercise Delays Brain Aging Through Regulation of the Mitochondrial Quality Control System. [PDF]
Biology (Basel)Zhu X, Shi L, Dong Y, Sun Y, Jin Q.
europepmc +1 more source