Results 211 to 220 of about 34,614 (273)
Role of recombinant S100A13 expression in regulating mitochondrial fission and fusion in lung epithelial cells. [PDF]
Alqattan S +5 more
europepmc +1 more source
Pyruvate Kinase M2 Mediates Apigenin‐Induced Energy Crisis and Apoptosis in Colon Cancer Cells
Apigenin, a dietary flavonoid with low toxicity, induces profound bioenergetic collapse in colon cancer cells by downregulating PKM2. This metabolic crisis, characterized by suppressed glycolysis and mitochondrial dysfunction, ultimately triggers robust apoptosis.
Ke Zhang +3 more
wiley +1 more source
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du +7 more
wiley +1 more source
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen +9 more
wiley +1 more source
Mitochondrial Metabolic Reprogramming in Colorectal Cancer-Associated Fibroblasts: An Up-to-Date Review. [PDF]
Li Y +4 more
europepmc +1 more source
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan +9 more
wiley +1 more source
From mechanisms to therapies: exploiting epigenetic and post-translational modifications of mitochondrial quality control in diabetic kidney disease. [PDF]
Zhao DM +4 more
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Targeting mitochondria as a potential therapeutic strategy against radioresistance in cancer. [PDF]
Nazam N +7 more
europepmc +1 more source
Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source

