Results 111 to 120 of about 1,253,804 (210)

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ida J. van der Klei, Walter Neupert, Neupert, Walter, Marten Veenhuis, Veenhuis, Marten, Klei, Ida J. van der   +5 more
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Alternative oxidase dependent respiration leads to an increased mitochondrial content in two long-lived mutants of the aging model Podospora anserina [PDF]

, 2011
The retrograde response constitutes an important signalling pathway from mitochondria to the nucleus which induces several genes to allow compensation of mitochondrial impairments.
Koen Houthoofd, Jacques R. Vanfleteren, Werner, Alexandra, Christian Q. Scheckhuber, De Vreese, Annemie, Scheckhuber Christian Q., Andrea C. Weil, Heinz D. Osiewacz, Jacques R Vanfleteren, Osiewacz, Heinz D., Scheckhuber, Christian Quintus, Christian Q Scheckhuber, De Vreese Annemie, Houthoofd Koen, Vanfleteren Jacques R., Vanfleteren, Jacques R., Weil Andrea C., Andrea C Weil, Werner Alexandra, Heinz D Osiewacz, Houthoofd, Koen, Osiewacz Heinz D., Alexandra Werner, Annemie De Vreese, Weil, Andrea C.   +24 more
core   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Efeitos da hiperglicemia crônica e seus metabólitos, metilglioxal e produtos terminais de glicação, na fisiologia e dinâmica mitocondrial no sistema nervoso central [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014.O diabetes mellitus (DM) é uma doença metabólica comum, caracterizada por um estado de hiperglicemia
Glaser, Viviane
core  

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Isolation and characterisation of the intermembrane space components of the mitochondrial TIM22 protein import machinery of Neurospora crassa [PDF]

, 2004
Mitochondria are essential cellular organelles of eukaryotic organisms, which import most of their proteinaceous constituents from the cytoplasm. Two mitochondrial membranes contain different translocation machineries which are involved in the import and
Vasiljev, Andreja
core   +1 more source

Multilayer Biobased Poly(ethylene furanoate)/Graphene Oxide Nanofibrous Membranes With Directional Water Transport for Efficient Microplastics Filtration

Advanced Materials Technologies, EarlyView.
A self‐assembled multilayer biobased PEF/GO nanofibrous membrane was developed by electrospinning for efficient PLA microplastics (MPs) filtration. The membrane combines superhydrophilicity, directional water transport, mechanical robustness, and a synergistic size‐exclusion interception and electrostatic repulsion MPs separation mechanism, enabling ...
Juraij Kandiyil, Sumayya Ansari, Prasanna Kumar S Mural, Yaser E. Greish, Adnan Younis, Akmal Nazir, Muhammad Z. Iqbal   +6 more
wiley   +1 more source

Mitochondrial Fusion Proteins and Human Diseases

Neurology Research International, 2013
Mitochondria are highly dynamic, complex organelles that continuously alter their shape, ranging between two opposite processes, fission and fusion, in response to several stimuli and the metabolic demands of the cell.
Michela Ranieri, Simona Brajkovic, Giulietta Riboldi, Dario Ronchi, Federica Rizzo, Nereo Bresolin, Stefania Corti, Giacomo P. Comi   +7 more
doaj   +1 more source