Results 101 to 110 of about 1,253,804 (210)

Modulation of Mitochondrial Dynamics in Primary Hippocampal Cultures of 5xFAD Mice by Mdivi-1, MFP, and Exogenous Zinc

Frontiers in Bioscience-Landmark
Background: Mitochondrial dynamics—the balance between fission, fusion, and mitophagy—are essential for maintaining cellular homeostasis and are increasingly implicated in the pathogenesis of Alzheimer’s disease (AD).
Alina Chaplygina, Daria Zhdanova
doaj   +1 more source

Medical image fusion: A survey of the state of the art [PDF]

, 2014
Medical image fusion is the process of registering and combining multiple images from single or multiple imaging modalities to improve the imaging quality and reduce randomness and redundancy in order to increase the clinical applicability of medical ...
James, Alex Pappachen, Alex Pappachen, James, Dasarathy, Belur V.   +2 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction

Frontiers in Aging Neuroscience, 2015
Mitochondrial dynamics is a term that encompasses the movement of mitochondria along the cytoskeleton, regulation of their architecture, and connectivity mediated by tethering and fusion/fission.
Antonio eZorzano, Marc eClaret
doaj   +1 more source

A New Bioactive Glass‐Based Hybrid Bioink With Enhanced Cell Viability and Antibacterial Properties

Advanced Healthcare Materials, EarlyView.
Graphical illustration of the production and characterization process, demonstrating the multiple functions of the new hybrid gelatin methacryloyl‐silver‐bioactive glass (GAB) material. Created in https://BioRender.com. ABSTRACT Recent advances in three‐dimensional bioprinting (3DBP) technology enable the production of customized bone substitutes ...
Adam C. Marsh, Ehsanul Hoque Apu, Theofania Kleisoura, Romila Manchanda, Valerie Johnson, Ginger Ross, Ioannis Tsamesidis, Eleana Kontonasaki, DeMarcus Bunn, Ahmet Erdem, Neal D. Hammer, Kurt D. Hankenson, Christopher H. Contag, Nureddin Ashammakhi, Xanthippi Chatzistavrou   +14 more
wiley   +1 more source

Design of Intense Neutron Source for Fusion Material Study and the Role of Universities [PDF]

, 1993
Need and requirement for the intense neutron source for fusion materials study have been discussed for many years. Recently, international climate has been becoming gradually maturing to consider this problem more seriously because of the recognition of ...
ISHINO, Shiori
core  

Multi-patterned dynamics of mitochondrial fission and fusion in a living cell. [PDF]

, 2012
Mitochondria are highly-dynamic organelles, but it is challenging to monitor quantitatively their dynamics in a living cell. Here we developed a novel approach to determine the global occurrence of mitochondrial fission and fusion events in living human ...
Lu, Shouqin, Chen, Ming, Shan Sicong, Quan Chen (163802), Zhang, Yan, Chen, Quan, Chuanmao Zhang, Chunsun Jiang (163786), Xiao, Weiming, Chen Juan, Long, Mian, Shan, Sicong, Shiqi Wang, Chen M, Lü Shouqin, Zhang, Chuanmao, Juan Chen, Chen Ming, Chen Quan, Yan Zhang, Mian Long, Weiming Xiao (163778), Ming Chen, Sicong Shan, 王世骐, Jiang, Chunsun, 吕守芹, Wang, SQ, 龙勉, Zhang Yan, 陈娟, 单思聪, Wang, Shiqi, Ming Chen (115604), Zhang CM, Wang Shiqi, Xiao WM, Shouqin Lü, Mian Long (163806), Yan Zhang (8098), Jiang Chunsun, Chunsun Jiang, Quan Chen, Zhang Chuanmao, Weiming Xiao, Juan Chen (61123), Jiang CS, Sicong Shan (163783), Long Mian, Chuanmao Zhang (163797), Shiqi Wang (163773), Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing, Peoples R China., Shouqin Lü (163792), Xiao Weiming, 章燕, Chen, Juan   +55 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Studies on D-3^He Fusion in LHD [PDF]

, 1996
In LHD ( Large Helical Device ) studies on realization of D-D fusion burning has been carried out, where tritium burning is out of this plan. We propose experiments on D-^3He fusion in this plan. This fueled fusion has the reaction cross-section as large
YAMAZAKI, Kozo, FUJIWARA, Masami, IIYOSHI, Atsuo, SUDO, Shigeru, MURAKAMI, Sadayoshi, KANNO, Ryutaro, TOMITA, Yukihiro, OHYABU, Nobuyoshi, SASAO, Mamiko, OKAMOTO, Masao, KANEKO, Osamu, TAKEIRI, Yasuhiko, MUTOH, Takashi   +12 more
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