Results 1 to 10 of about 53,504 (295)

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

open access: yesNeurobiology of Disease, 2016
Mitochondria are dynamic organelles that continually move, fuse and divide. The dynamic balance of fusion and fission of mitochondria determines their morphology and allows their immediate adaptation to energetic needs, keeps mitochondria in good health ...
A.M. Bertholet   +11 more
doaj   +5 more sources

Roles of mitochondrial fusion and fission in breast cancer progression: a systematic review [PDF]

open access: yesWorld Journal of Surgical Oncology, 2022
Background Mitochondria play critical roles in cellular physiological activity as cellular organelles. Under extracellular stimulation, mitochondria undergo constant fusion and fission to meet different cellular demands. Mitochondrial dynamics, which are
Jixiang Xing   +5 more
doaj   +2 more sources

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

open access: yesMembranes, 2022
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi   +2 more
doaj   +3 more sources

Mitochondrial fusion–fission dynamics and its involvement in colorectal cancer

open access: yesMolecular Oncology
The incidence and mortality rates of colorectal cancer have elevated its status as a significant public health concern. Recent research has elucidated the crucial role of mitochondrial fusion–fission dynamics in the initiation and progression of ...
Zihong Wu   +5 more
doaj   +4 more sources

Mitochondrial morphological features are associated with fission and fusion events. [PDF]

open access: yesPLoS ONE, 2014
Mitochondria are dynamic organelles that undergo constant remodeling through the regulation of two opposing processes, mitochondrial fission and fusion.
Laura M Westrate   +4 more
doaj   +4 more sources

Mitochondrial dynamism and heart disease: changing shape and shaping change [PDF]

open access: yesEMBO Molecular Medicine, 2015
Mitochondria of adult cardiomyocytes appear hypo‐dynamic, lacking interconnected reticular networks and the continual fission and fusion observed in many other cell types.
Gerald W Dorn
doaj   +3 more sources

The Role of Abnormal Mitochondrial Fusion and Fission in the Inflammatory Senescence of Dental Pulp Stem Cells [PDF]

open access: yesInternational Dental Journal
Aim: The regeneration ability of dental pulp stem cells (DPSCs) is essential for vital pulp preservation therapy, but may be disrupted by inflammatory senescence.
Wenyue Tang   +9 more
doaj   +2 more sources

Mitochondrial fission and fusion in inflammatory diseases: mechanisms and therapeutic implications [PDF]

open access: yesJournal of Translational Medicine
Background Mitochondrial fission and fusion are dynamic and highly regulated processes that are essential for maintaining cellular homeostasis. These processes are regulated by core proteins, including dynamin-related protein 1 (DRP1), fission 1 protein (
Wenjing Xu   +4 more
doaj   +2 more sources

MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries

open access: yesBMC Biology, 2021
Background Mitochondrial dynamics is the result of a dynamic balance between fusion and fission events, which are driven via a set of mitochondria-shaping proteins.
Rong Yu   +6 more
doaj   +1 more source

The Imbalance of Mitochondrial Fusion/Fission Drives High-Glucose-Induced Vascular Injury

open access: yesBiomolecules, 2021
Emerging evidence shows that mitochondria fusion/fission imbalance is related to the occurrence of hyperglycemia-induced vascular injury. To study the temporal dynamics of mitochondrial fusion and fission, we observed the alteration of mitochondrial ...
Yunsi Zheng, Anqi Luo, Xiaoquan Liu
doaj   +1 more source

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