Results 271 to 280 of about 156,551 (297)
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Mitochondrial fusion and inheritance of the mitochondrial genome
Journal of Plant Research, 2010Although maternal or uniparental inheritance of mitochondrial genomes is a general rule, biparental inheritance is sometimes observed in protists and fungi,including yeasts. In yeast, recombination occurs between the mitochondrial genomes inherited from both parents.Mitochondrial fusion observed in yeast zygotes is thought to set up a space for DNA ...
Hiroyoshi, Takano +2 more
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2007
The field of mitochondrial dynamics has received a great deal of attention as a result of a number of studies linking mitochondrial fission and fusion machinery to apoptosis. Specifically, elevated levels of mitochondrial fission or compromised mitochondrial fusion can sensitize cells to apoptotic stimuli.
Shelly L, Meeusen, Jodi, Nunnari
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The field of mitochondrial dynamics has received a great deal of attention as a result of a number of studies linking mitochondrial fission and fusion machinery to apoptosis. Specifically, elevated levels of mitochondrial fission or compromised mitochondrial fusion can sensitize cells to apoptotic stimuli.
Shelly L, Meeusen, Jodi, Nunnari
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Regulation of mitochondrial fusion and division
Trends in Cell Biology, 2007In many organisms, ranging from yeast to humans, mitochondria fuse and divide to change their morphology in response to a multitude of signals. During the past decade, work using yeast and mammalian cells has identified much of the machinery required for fusion and division, including the dynamin-related GTPases--mitofusins (Fzo1p in yeast) and OPA1 ...
Kara L, Cerveny +4 more
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New Beginnings: Mitochondrial Renewal by Massive Mitochondrial Fusion
Trends in Plant Science, 2017Massive mitochondrial fusion (MMF) in germinating arabidopsis seeds, together with earlier studies, suggests a significant role for MMF in the life cycle of flowering plants. MMF is likely to facilitate nucleoid transmission, mitochondrial DNA (mtDNA) recombination, and the homogenization of mitochondrial components, thus providing a type of quality ...
Ray J, Rose, David W, McCurdy
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Current Genetics, 1996
A specific linear mitochondrial plasmid (mF) is genetically associated with the fusion of mitochondria in the true slime mould, Physarum polycephalum. In matings between mF+ and mF- strains, which respectively carry and do not carry the mF plasmid, mitochondrial fusion occurs in the zygote.
H, Takano +3 more
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A specific linear mitochondrial plasmid (mF) is genetically associated with the fusion of mitochondria in the true slime mould, Physarum polycephalum. In matings between mF+ and mF- strains, which respectively carry and do not carry the mF plasmid, mitochondrial fusion occurs in the zygote.
H, Takano +3 more
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Reciprocal Regulation of Mitochondrial Fission and Fusion
Trends in Biochemical Sciences, 2020The dynamic processes of mitochondrial fission and fusion are tightly regulated, determine mitochondrial shape, and influence mitochondrial functions. For example, fission and fusion mediate energy output, production of reactive oxygen species (ROS), and mitochondrial quality control.
Rasha Sabouny, Timothy E. Shutt
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Mitochondrial Fission and Fusion in Human Diseases
New England Journal of Medicine, 2014no ...
Sanchis-Gomar, F, Derbré, Frédéric
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Mitochondrial fusion and fission in the control of apoptosis
Trends in Cell Biology, 2005Mitochondrial outer membrane permeabilization (MOMP) determines the point-of-no-return of most if not all signal-transduction cascades leading to cell death. It has been postulated that the molecular mechanism leading to MOMP could depend on the activation of the mitochondrial fission machinery mediated by proteins from the dynamin superfamily. However,
Jean-Luc, Perfettini +2 more
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Mitochondrial Fusion Intermediates Revealed in Vitro
Science, 2004The events that occur during the fusion of double-membraned mitochondria are unknown. As an essential step toward determining the mechanism of mitochondrial fusion, we have captured this event in vitro. Mitochondrial outer and inner membrane fusion events were separable and mechanistically distinct, but both required guanosine 5′-triphosphate ...
Shelly, Meeusen +2 more
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Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases
New England Journal of Medicine, 2013Mitochondria fuse and divide in response to cell demands and environment. Alterations in mitochondrial dynamics underlie various human diseases, including cancer and neurologic and cardiovascular diseases. Defining the alterations may identify potential therapeutic targets.
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