Results 1 to 10 of about 350,705 (311)
Transport of proteins across mitochondrial membranes [PDF]
The Clinical Investigator, 1994 The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes
Neupert, Walter
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Protein Quality Control at the Mitochondrial Surface
Frontiers in Cell and Developmental Biology, 2021 Mitochondria contain two membranes, the outer and inner membrane. The outer membrane fulfills crucial functions for the communication of mitochondria with the cellular environment like exchange of lipids via organelle contact sites, the transport of ...
Fabian den Brave +2 more
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Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters [PDF]
Journal of Biological Chemistry, 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Although
Adrian Taylor +3 more
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Molecules, 2021 The functioning of mitochondria and their biogenesis are largely based on the proper function of the mitochondrial outer membrane channels, which selectively recognise and import proteins but also transport a wide range of other molecules, including ...
Monika Mazur +2 more
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Identification of a Membrane Protein Involved in Mitochondrial Phosphate Transport [PDF]
European Journal of Biochemistry, 1976 A specific labeling by radioactive N‐ethylmaleimide of a protein involved in phosphate transport was obtained by protecting one of the two ‐SH groups of the transport system with low concentrations of mersalyl. Subsequently, the other free ‐SH groups were blocked with excess N‐ethylmaleimide.
P, Hadvary, B, Kadenbach
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Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals. [PDF]
PLoS ONE, 2013 Steroidogenesis begins with the transport of cholesterol from intracellular stores into mitochondria via a series of protein-protein interactions involving cytosolic and mitochondrial proteins located at both the outer and inner mitochondrial membranes ...
Jinjiang Fan, Vassilios Papadopoulos
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eLife, 2022 Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting ...
Holly C Ford +5 more
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Mitochondrial Volume Regulation and Swelling Mechanisms in Cardiomyocytes
Antioxidants, 2023 Mitochondrion, known as the “powerhouse” of the cell, regulates ion homeostasis, redox state, cell proliferation and differentiation, and lipid synthesis. The inner mitochondrial membrane (IMM) controls mitochondrial metabolism and function. It possesses
Xavier R. Chapa-Dubocq +3 more
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A dynamic model of the mitochondrial protein import machinery [PDF]
, 1992 Many proteins are translocated into or across two mem-branes in order to reach their functional destination; these include many nuclear-encoded mitochondrial and chloro-plast proteins, as well as proteins transported into or across the outer membrane of ...
Baker +24 more
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Biomolecules, 2021 The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes the transport of short, medium and long carbon chain acyl-carnitines across the mitochondrial inner membrane in exchange for carnitine.
Annamaria Tonazzi +4 more
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