Results 41 to 50 of about 98,042 (158)

Biological sex does not impact intrinsic mitochondrial respiration supported by complexes I and II in human skeletal muscle

Experimental Physiology
The effect of biological sex on rates of skeletal muscle mitochondrial respiration supported by creatine‐dependent phosphate shuttling was previously unknown.
Emily J. Ferguson, Lauren J. Pacitti, Justin Bureau, Callum J. Pufahl, Eveline Menezes, Tanner Stokes, Shivam Gandhi, Luca J. Delfinis, Craig A. Simpson, Christopher G. R. Perry, Brendon J. Gurd, Chris McGlory   +11 more
doaj   +1 more source

A simple method for mitochondrial respiration and calcium uptake assessment in pollen tubes

MethodsX, 2019
Key mitochondrial processes are known to be widely conserved throughout the eukaryotic domain. However, the scarce availability of working materials may restrict the assessment of such mitochondrial activities in several working models.
Diana J. Ortiz-Jiménez, Casandra M. López-Aquino, Cesar Flores-Herrera, Gisela Preciado-Linares, Israel Gonzalez-Vizueth, Roeb García-Arrazola, Daniela Araiza-Olivera, Manuel Gutiérrez-Aguilar   +7 more
doaj   +1 more source

Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis [PDF]

, 2003
We have shown here that the apoptosis inducer staurosporine causes an early decrease in the endogenous respiration rate in intact 143B.TK- cells. On the other hand, the activity of cytochrome c oxidase is unchanged for the first 8 h after staurosporine ...
Attardi, Giuseppe, Chomyn, Anne, Duan, Shili, Hájek, Petr, Lin, Catherine, Shin, Soo Kyung   +5 more
core  

Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene [PDF]

, 2001
The gene for the single subunit, rotenone-insensitive, and flavone-sensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae (NDI1) can completely restore the NADH dehydrogenase activity in mutant human cells that lack the essential ...
Attardi, Giuseppe, Bai, Yidong, Chan, Elisa, Chomyn, Anne, Hájek, Petr, Matsuno-Yagi, Akemi, Seo, Byoung Boo, Yagi, Takao   +7 more
core   +1 more source

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin [PDF]

, 2020
High expression of Ki67, a proliferation marker, is associated with reduced endometrial cancer-specific survival. Pre-surgical metformin reduces tumour Ki-67 expression in some women with endometrial cancer. Metformin's anti-cancer activity may relate to
Crosbie, EJ, Finegan, KG, Kitson, S, Latif, A, Lisanti, MP, Marshall, K, McVey, R, Sivalingam, VN, Sotgia, F, Stratford, IJ   +9 more
core   +2 more sources

Reduced Citrate Synthase Activity Effect on Oxygen Consumption Rates in Isolated Mitochondria from Mice Liver and Muscles

Baltic Journal of Sport and Health Sciences, 2018
Background. Liver and skeletal muscles play the major role in metabolism. Mitochondria are of particular importance in functioning of these organs.
Andrej Fokin, Rasa Žūkienė, Aivaras Ratkevičius   +2 more
doaj   +1 more source

Sex differences and estrogen effects in cardiac mitochondria in human aortic stenosis and in the mouse heart

Frontiers in Endocrinology, 2023
IntroductionSex differences in the adaptation to pressure overload have been described in humans, as well as animal models, and have been related to sex-specific expression of mitochondrial genes.
Daniela Fliegner, Daniela Fliegner, Alexandra Ellieva, Anja Angelov, Georgi Petrov, Vera Regitz-Zagrosek, Vera Regitz-Zagrosek   +6 more
doaj   +1 more source

Research note: using rapid adjustments of mitochondrial function to dietary changes as an indicator? an experimental test in slower growing broiler hybrid

Poultry Science
This study investigated the effects of dietary energy and lysine levels on mitochondrial respiration and its association with growth performance in slower-growing broiler chickens.
Ali Kiani, Heidi Högel, Suvi Ruuskanen
doaj   +1 more source

Recombinant Mitochondrial Transcription Factor A with N-terminal Mitochondrial Transduction Domain Increases Respiration and Mitochondrial Gene Expression in G11778A Leber's Hereditary Optic Neuropathy Cybrid Cells [PDF]

, 2008
Diseases involving mitochondrial defects usually manifest themselves in high-energy, post-mitotic tissues such as brain, retina, skeletal and cardiac muscle and frequently cause deficiencies in mitochondrial bioenergetics.
Caitlin K. Quigley, Francisco R. Portell, James P. Bennett, Lisa D. Dunahm, Ravindar R. Thomas, Shilpa Iyer   +5 more
core   +1 more source

Methionine supplementation stimulates mitochondrial respiration

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2018
Mitochondria play essential metabolic functions in eukaryotes. Although their major role is the generation of energy in the form of ATP, they are also involved in maintenance of cellular redox state, conversion and biosynthesis of metabolites and signal transduction.
Tripodi, F, Castoldi, A, Nicastro, R, Reghellin, V, Lombardi, L, Airoldi, C, Falletta, E, Maffioli, E, Scarcia, P, Palmieri, L, Alberghina, L, Agrimi, G, Tedeschi, G, Coccetti, P   +13 more
openaire   +3 more sources