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Mitofusin 2 Inhibits Mitochondrial Antiviral Signaling
Science Signaling, 2009A protein that mediates mitochondrial fusion also suppresses innate immune responses to viral infection.
Kai, Yasukawa +7 more
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Mitofusin-2 Regulates Platelet Mitochondria and Function
Circulation ResearchBACKGROUND: Single-nucleotide polymorphisms linked with the rs1474868 T allele ( MFN2 [mitofusin-2] T/T) in the human mitochondrial fusion protein MFN2 gene are associated with reduced platelet MFN2 RNA expression and platelet ...
Shancy Jacob +27 more
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The Role of Mitofusins in the Osteoclast Lineage
2019Mitochondria exist in a highly dynamic network in many cell types, and mutations in mitochondrial transmembrane GTPase mitofusin2 (MFN2), a key factor that mediates mitochondrial tethering, cause defects in the nervous system. Intriguingly, the skeleton has been overlooked in patients with such mutations.
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E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response
Molecular Cell, 2023Vincent Anton +2 more
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Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity
Virulence, 2021In Soo Kim +2 more
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Research Progress of Mitofusin-2*
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2010Guang-Ju ZHAO +2 more
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Cell and Tissue Research, 2007 Mitofusin gain and loss of function drive pathogenesis in Drosophila models of CMT 2A neuropathy
EMBO Reports, 2018Manuel Rojo +2 more
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