Results 151 to 160 of about 3,343 (171)

Charcot-Marie-Tooth type 2A variants of mitofusin 2 sensitize cells to apoptotic cell death. [PDF]

J Cell Sci
Joaquim M, Bulimaga MB, Mohn MA, Plouzennec S, Osinski L, Altin S, Mahabir E, Chevrollier A, Escobar-Henriques M.   +8 more
europepmc   +1 more source

Mitochondrial targeting strategies for mitigating oxidative damage and enhancing neuroprotection in ischemic stroke: A Review. [PDF]

IBRO Neurosci Rep
Trujillo-Rangel WÁ, Escutia-Gutiérrez R, García-Benavides L, Zamudio-Ojeda A, Delgado-Lara DLC, García-Mercado FG, Padilla-Ponce DJ, Magallón-Chávez O, Rivas-Loaiza JA, Pérez-Cisneros M, Guevara-Martínez SJ.   +10 more
europepmc   +1 more source

Cyclic Altitude Training, Mitochondrial Health, and the Oral-Airway Axis: Intermittent Hypoxia Between Adaptation and Disease. [PDF]

J Clin Med
Cannon M, Peldyak J, Reynolds PR, Bikman B.   +3 more
europepmc   +1 more source

Subcellular mitochondrial heterogeneity enables opposing metabolic demands. [PDF]

Trends Endocrinol Metab
Chen B, Shah YM, Lyssiotis CA.
europepmc   +1 more source

Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2.

J Cell Sci
Narendradev ND, Ravindran R, Jain P, Chaudhary S, Velikkakath AKG, Sudharman A, Janardhanan A, Nag TC, Yadav SC, Srinivasula SM.   +9 more
europepmc   +1 more source

Calcium Signalling: Mitofusins Promote Interorganellar Crosstalk [PDF]

Current Biology, 2009
SummaryJuxtaposition of the endoplasmic reticulum with mitochondria facilitates Ca2+ fluxes between the organelles. However, the molecular basis of interorganellar tethering remains unknown.
Anant B. Parekh
exaly   +2 more sources

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion [PDF]

Molecular Biology of the Cell, 2009
Mitochondrial fusion requires the coordinated fusion of the outer and inner membranes. Three large GTPases—OPA1 and the mitofusins Mfn1 and Mfn2—are essential for the fusion of mammalian mitochondria.
David C Chan, Zhiyin Song, Terrence G Frey   +2 more
exaly   +1 more source

Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity [PDF]

Cell, 2013
SummaryMitochondria are key organelles in the maintenance of cellular energy metabolism and integrity. Here, we show that mitochondria number decrease but their size increase in orexigenic agouti-related protein (Agrp) neurons during the transition from ...
Marcelo O Dietrich, Tamas L Horvath, Zhomg-Wu Liu   +2 more
exaly   +2 more sources

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development [PDF]

Journal of Cell Biology, 2003
Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown.
Erik E Griffin, David C Chan, Andrew J Ewald   +2 more
exaly   +2 more sources

Mitofusins, from Mitochondria to Metabolism

Molecular Cell, 2016
Luca Scorrano, Emilie Schrepfer
exaly   +2 more sources