Results 11 to 20 of about 386,071 (373)

Mitosis Counting in Breast Cancer: Object-Level Interobserver Agreement and Comparison to an Automatic Method. [PDF]

open access: yesPLoS ONE, 2016
Tumor proliferation speed, most commonly assessed by counting of mitotic figures in histological slide preparations, is an important biomarker for breast cancer.
Mitko Veta   +4 more
doaj   +2 more sources

53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis

open access: yeseLife, 2016
Mitosis occurs efficiently, but when it is disturbed or delayed, p53-dependent cell death or senescence is often triggered after mitotic exit. To characterize this process, we conducted CRISPR-mediated loss-of-function screens using a cell-based assay in
Chii Shyang Fong   +7 more
doaj   +2 more sources

Assessment of algorithms for mitosis detection in breast cancer histopathology images [PDF]

open access: yesMedical Image Anal., 2014
The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers.
Adnan M. Khan   +59 more
core   +7 more sources

Regulation of mRNA translation during mitosis

open access: yeseLife, 2015
Passage through mitosis is driven by precisely-timed changes in transcriptional regulation and protein degradation. However, the importance of translational regulation during mitosis remains poorly understood. Here, using ribosome profiling, we find both
Marvin E Tanenbaum   +3 more
doaj   +2 more sources

Whole-Slide Mitosis Detection in H&E Breast Histology Using PHH3 as a Reference to Train Distilled Stain-Invariant Convolutional Networks [PDF]

open access: yesIEEE Transactions on Medical Imaging, 2018
Manual counting of mitotic tumor cells in tissue sections constitutes one of the strongest prognostic markers for breast cancer. This procedure, however, is time-consuming and error-prone.
David Tellez   +12 more
semanticscholar   +1 more source

Data on motivational factors of the medical and nursing staff of a Greek Public Regional General Hospital during the economic crisis

open access: yesData in Brief, 2017
In this article, we present the data related to motivational factors given by the medical (n=118) and nursing (n=217) staff, of a Greek Public General Hospital during a period of financial austerity.
Marianna Charalambous   +2 more
doaj   +1 more source

Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]

open access: yes, 2011
Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Cross, R. A.   +2 more
core   +2 more sources

Chromosome Oscillations in Mitosis [PDF]

open access: yes, 2005
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar   +8 more
core   +2 more sources

Characteristics of mitosis in the gametophyte cells of the marine green alga Monostroma angicava

open access: yesBotanical Studies, 2019
Background Some marine algae exhibit several characteristics of mitosis (e.g., the timing of mitosis such as diurnal periodicity) that are unique from those of land plants.
Yusuke Horinouchi, Tatsuya Togashi
doaj   +1 more source

Positive Feedback Keeps Duration of Mitosis Temporally Insulated from Upstream Cell-Cycle Events [PDF]

open access: yes, 2016
Cell division is characterized by a sequence of events by which a cell gives rise to two daughter cells. Quantitative measurements of cell-cycle dynamics in single cells showed that despite variability in G1-, S-, and G2 phases, duration of mitosis is ...
Araujo, AR   +3 more
core   +1 more source

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