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Mitosis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Diplomová práce Mitosis je figurální plastika vytvořená pomocí duplikace sochy. Tyto duplikáty tvoří páry jež se na sebe mitoticky vážou. Páry jsou komponovány do spletité soustavy a tvoří tak kulovitý objekt.
Ducháček, Ladislav
core   +5 more sources

Triggering mitosis [PDF]

open access: yesFEBS Letters, 2019
Entry into mitosis is triggered by the activation of cyclin‐dependent kinase 1 (Cdk1). This simple reaction rapidly and irreversibly sets the cell up for division.
Adrijana Crncec, H. Hochegger
semanticscholar   +3 more sources

Mitosis Counting in Breast Cancer: Object-Level Interobserver Agreement and Comparison to an Automatic Method. [PDF]

open access: yesPLoS ONE, 2016
Tumor proliferation speed, most commonly assessed by counting of mitotic figures in histological slide preparations, is an important biomarker for breast cancer.
Mitko Veta   +4 more
doaj   +2 more sources

53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis

open access: yeseLife, 2016
Mitosis occurs efficiently, but when it is disturbed or delayed, p53-dependent cell death or senescence is often triggered after mitotic exit. To characterize this process, we conducted CRISPR-mediated loss-of-function screens using a cell-based assay in
Chii Shyang Fong   +7 more
doaj   +2 more sources

Assessment of algorithms for mitosis detection in breast cancer histopathology images [PDF]

open access: yesMedical Image Anal., 2014
The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers.
Adnan M. Khan   +59 more
core   +7 more sources

Regulation of mRNA translation during mitosis

open access: yeseLife, 2015
Passage through mitosis is driven by precisely-timed changes in transcriptional regulation and protein degradation. However, the importance of translational regulation during mitosis remains poorly understood. Here, using ribosome profiling, we find both
Marvin E Tanenbaum   +3 more
doaj   +2 more sources

Stressing Mitosis to Death [PDF]

open access: yesFrontiers in Oncology, 2014
The final stage of cell division (mitosis), involves the compaction of the duplicated genome into chromatid pairs. Each pair is captured by microtubules emanating from opposite spindle poles, aligned at the metaphase plate, and then faithfully segregated
Andrew eBurgess   +3 more
doaj   +4 more sources

Phosphorylation and Chromatin Tethering Prevent cGAS activation During Mitosis

open access: yesScience, 2021
Keeping cGAS silent Cells detect microbial and self-DNA in the cytosol as a danger signal that triggers immune and inflammatory responses. Paradoxically, a large fraction of a DNA-sensing enzyme called cGAS is tightly associated with the chromatin ...
Tuo Li   +6 more
semanticscholar   +1 more source

Actin cables and comet tails organize mitochondrial networks in mitosis

open access: yesNature, 2021
Symmetric cell division requires the even partitioning of genetic information and cytoplasmic contents between daughter cells. Whereas the mechanisms coordinating the segregation of the genome are well known, the processes that ensure organelle ...
Andrew S. Moore   +13 more
semanticscholar   +1 more source

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